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Filtering by: Creator Roth, Anna M. Academic Affiliation Forest Ecosystems and Society License Attribution 3.0 United States

What the Inbred Scandinavian Wolf Population Tells Us about the Nature of Conservation

Creator:

Räikkönen, Jannikke, Vucetich, John A., Vucetich, Leah M., Peterson, Rolf O., and Nelson, Michael P.

Abstract:

The genetic aspects of population health are critical, but frequently difficult to assess. Of concern has been the genetic constitution of Scandinavian wolves (Canis lupus), which represent an important case in conservation. We examined the incidence of different congenital anomalies for 171 Scandinavian wolves, including the immigrant founder female, born...

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Tells Us about the Nature of Conservation Jannikke Räikkönen1*, John A. Vucetich2, Leah M. Vucetich2
Simulated Evolution of Protein-Protein Interaction Networks with Realistic Topology

Creator:

Peterson, G. Jack, Pressé, Steve, Peterson, Kristin S., and Dill, Ken A.

Abstract:

We model the evolution of eukaryotic protein-protein interaction (PPI) networks. In our model, PPI networks evolve by two known biological mechanisms: (1) Gene duplication, which is followed by rapid diversification of duplicate interactions. (2) Neofunctionalization, in which a mutation leads to a new interaction with some other protein. Since many...

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selection. In our model, NE mutations occur at a rate m, which is assumed to be constant. All proteins are