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Filtering by: Academic Affiliation Microbiology Creator Szymanski, Maciej

Organelle trafficking of chimeric ribozymes and genetic manipulation of mitochondria

Creator:

Val, Romain, Wyszko, Eliza, Valentin, Clarisse, Szymanski, Maciej, Cosset, Anne, Alioua, Malek, Dreher, Theo W., Barciszewski, Jan, and Dietrich, Andre

Abstract:

With the expansion of the RNA world, antisense strategies have become widespread to manipulate nuclear gene expression but organelle genetic systems have remained aside. The present work opens the field to mitochondria. We demonstrate that customized RNAs expressed from a nuclear transgene and driven by a transfer RNA-like (tRNA-like) moiety...

Resource Type:

Article