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Filtering by: Advisor Vella, Anthony T. Remove constraint Advisor: Vella, Anthony T. Academic Affiliation Microbiology Remove constraint Academic Affiliation: Microbiology Degree Field Microbiology Remove constraint Degree Field: Microbiology

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  • The role of costimulation and adjuvants in the development of T cell effector and memory responses

    Creator:
    Maxwell, Joseph R.
    Abstract:
    T cells are one of the key cells in the immune system. Although they are not the first line of defense against a pathogen, their functions can greatly enhance the phagocytosis and destruction of pathogens as well as the development of antibody responses. Furthermore, even when responding T cells have...
    Resource Type:
    Dissertation
    Full Text:
    Kerkvliet provided funding and facilities for the work performed by Carl Ruby. Anthony T. Vella was the

  • Uncovering the mechanism of IL-4-mediated T cell survival

    Creator:
    Moscibrocki, Cathleen M.
    Abstract:
    Although IL-4 is a well-characterized multi-functional cytokine, its role as a survival factor in T cells is not completely understood. In an attempt to uncover IL-4-mediated survival, we studied caspase activation in primary mouse T lymphocytes undergoing death by neglect, activation-induced or steroid-induced cell death. Here, we identify the executioner...
    Resource Type:
    Masters Thesis
    Full Text:
    of IL-4-mediated T Cell Survival. Abstract approved: Anthony T. Vella Although IL-4 is a well