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Filtering by: Creator Silva, George Academic Affiliation Microbiology Peer Reviewed Yes

A high level of liver-specific expression of oncogenic KrasV12 drives robust liver tumorigenesis in transgenic zebrafish

Creator:

Nguyen, Anh Tuan, Emelyanov, Alexander, Koh, Chor Hui Vivien, Spitsbergen, Jan M., Lam, Siew Hong, Mathavan, Sinnakaruppan, Parinov, Serguei, and Gong, Zhiyuan

Abstract:

Human liver cancer is one of the deadliest cancers worldwide, with hepatocellular carcinoma (HCC) being the most common type. Aberrant Ras signaling has been implicated in the development and progression of human HCC, but a complete understanding of the molecular mechanisms of this protein in hepatocarcinogenesis remains elusive. In this...

Resource Type:

Article