Index Catalog // ScholarsArchive@OSU

Creator:: Payet, Jérôme P., McMinds, Ryan, Burkepile, Deron E., and Thurber, Rebecca L. Vega
Abstract:: Despite nutrient-depleted conditions, coral reef waters harbor abundant and diverse microbes; as major agents of microbial mortality, viruses are likely to influence microbial processes in these ecosystems. However, little is known about marine viruses in these rapidly changing ecosystems. Herewe examined spatial and short-term temporal variability in marine viral abundance...
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Full Text:: ., McMinds, R., Burkepile, D. E., & Vega Thurber, R. L. (2014). Unprecedented evidence for high viral

Creator:: Brandt, Marilyn E., Smith, Tyler B., Correa, Adrienne M. S., and Vega-Thurber, Rebecca
Abstract:: In September of 2010, Brewer's Bay reef, located in St. Thomas (U.S. Virgin Islands), was simultaneously affected by abnormally high temperatures and the passage of a hurricane that resulted in the mass bleaching and fragmentation of its coral community. An outbreak of a rapid tissue loss disease among coral colonies...
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Full Text:: Driver of a Coral Disease Outbreak Marilyn E. Brandt1*, Tyler B. Smith1, Adrienne M. S. Correa2,3,4

Creator:: Thurber, Rebecca Vega, Burkepile, Deron E., Correa, Adrienne M. S., Thurber, Andrew R., Shantz, Andrew A., Welsh, Rory, Pritchard, Catharine, and Rosales, Stephanie
Abstract:: With the continued and unprecedented decline of coral reefs worldwide, evaluating the factors that contribute to coral demise is of critical importance. As coral cover declines, macroalgae are becoming more common on tropical reefs. Interactions between these macroalgae and corals may alter the coral microbiome, which is thought to play...
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Full Text:: Microbial Community Structure of the Reef-Building Coral, Porites astreoides Rebecca Vega Thurber1,2*, Deron

Creator:: Zhan, Huiqing, Spitsbergen, Jan, Qing, Wei, Wu, Yi Lian, Paul, Thomas A., Casey, James W., and Gong, Zhiyuan
Abstract:: A retrovirus homologue gene of cellular cyclin D₁, walleye dermal sarcoma virus rv-cyclin gene (orf A or rv-cyclin), was expressed in the livers of zebrafish under the control of liver fatty-acid binding protein (lfabp) promoter. To prevent possible fatality caused by over-expression of the oncogene, the GAL4/UAS system was used...
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Full Text:: 67792486 E-mail address: dbsgzy@nus.edu.sg. 2 Abstract A retrovirus homologue gene of

Creator:: Nguyen, Anh Tuan, Emelyanov, Alexander, Koh, Chor Hui Vivien, Spitsbergen, Jan M., Parinov, Serguei, and Gong, Zhiyuan
Abstract:: Because Ras signaling is frequently activated by major hepatocellular carcinoma etiological factors, a transgenic zebrafish constitutively expressing the kras(V12) oncogene in the liver was previously generated by our laboratory. Although this model depicted and uncovered the conservation between zebrafish and human liver tumorigenesis, the low tumor incidence and early mortality...
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Full Text:: Zhiyuan Gong1,‡ RESEARCH ARTICLE D ise as e M od el s & M ec ha ni sm s D M M

Creator:: Li, Zhen, Zheng, Weiling, Wang, Zhengyuan, Zeng, Zhiqiang, Zhan, Huiqing, Li, Caixia, Zhou, Li, Yan, Chuan, Spitsbergen, Jan M., and Gong, Zhiyuan
Abstract:: Myc is a pleiotropic transcription factor that is involved in many cellular activities relevant to carcinogenesis, including hepatocarcinogenesis. The zebrafish has been increasingly used to model human diseases and it is particularly valuable in helping to identify common and conserved molecular mechanisms in vertebrates. Here we generated a liver tumor...
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Full Text:: ise as e M od el s & M ec ha ni sm s D M M Disease Models & Mechanisms 415 Myc

Creator:: Nguyen, Anh Tuan, Emelyanov, Alexander, Koh, Chor Hui Vivien, Spitsbergen, Jan M., Lam, Siew Hong, Mathavan, Sinnakaruppan, Parinov, Serguei, and Gong, Zhiyuan
Abstract:: Human liver cancer is one of the deadliest cancers worldwide, with hepatocellular carcinoma (HCC) being the most common type. Aberrant Ras signaling has been implicated in the development and progression of human HCC, but a complete understanding of the molecular mechanisms of this protein in hepatocarcinogenesis remains elusive. In this...
Resource Type:: Article
Full Text:: Zhiyuan Gong1,* RESEARCH ARTICLE D ise as e M od el s & M ec ha ni sm s D M M

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