Index Catalog // ScholarsArchive@OSU

Cloning and biochemical characterization of the hectochlorin biosynthetic gene cluster from the marine cyanobacterium Lyngbya majuscula

Creator:: Ramaswamy, Aishwarya V.
Abstract:: Cyanobacteria are rich in biologically active secondary metabolites, many of which have potential application as anticancer or antimicrobial drugs or as useful probes in cell biology studies. A Jamaican isolate of the marine cyanobacterium, Lyngbya majuscula was the source of a novel antifungal and cytotoxic secondary metabolite, hectochlorin. The structure...
Resource Type:: Dissertation
Full Text:: Zabriskie, Dr. Steve Giovannoni, Dr. George Constantine and Dr. Jeff Stone for their assistance. 11 am

Impacts of Environmental Change on a Newly-characterized Symbiosis between a Novel Bacterial Parasite, Genus Aquarickettsia, and the Coral Acropora cervicornis

Creator:: Klinges, J. Grace
Abstract:: Coral reef ecosystems continue to be significantly altered by disease epizootics, but why some host populations remain resistant while others succumb to outbreaks remains unknown. Research across diverse animal and plant host systems has revealed that disease severity is strongly influenced by host genetics and by environmental influences on both...
Resource Type:: Dissertation

Chemical and Genetic Investigations of Toxic Freshwater Cyanobacterial Blooms for Improved Monitoring and Understanding of Lake Ecology

Creator:: Collart, Lindsay P.
Abstract:: Toxin production by cyanobacterial harmful algal blooms (cyanoHABs) in freshwater systems has lasting ecological and human impacts. Nutrients, light availability, hydrology, and microbial community composition impact the frequency and intensity of toxic cyanoHABs. Climate change will exacerbate toxic cyanoHABs, making real time and predictive monitoring a vital tool for managing...
Resource Type:: Dissertation

Effects of Anthropogenic Stressors on Seagrass and Coral Microbiomes

Creator:: Wang, Lu
Abstract:: Seagrasses and coral reefs play important roles in nutrient cycling, coastal protection, and maintaining marine biodiversity. However, these coastal marine organisms are declining globally due to anthropogenic stressors, such as rising ocean temperatures, ocean acidification, and eutrophication. These organisms live in close association with their microbiomes, which can be beneficial...
Resource Type:: Dissertation
Full Text:: in eutrophication and increased temperature (Kilminster and Garland 2009; George et al. 2020

Establishment and dynamics of methane-oxidizing microbial communities in marine sediments

Creator:: Klasek, Scott A.
Abstract:: Marine sediments are vast sources and reservoirs of methane, a potent greenhouse gas. Most of this methane is anaerobically oxidized by archaea before it can reach the overlying ocean, though the efficiency of this process often depends on methane fluxes and mechanisms of fluid transport. Anaerobic methanotrophic archaea, or ANME,...
Resource Type:: Dissertation
Full Text:: comments, suggestions, and ideas. I would also like to recognize Simon Gilroy, Sarah Swanson, George

Host-pathogen Interactions of Respiratory RNA Viruses and the Application of Recombinase Polymerase Amplification for Viral Diagnostics

Creator:: Prescott, Meagan A.
Abstract:: Humans and viral disease are inextricably intertwined. Viral disease plays an immeasurable role in human life, from the disease and economic burden associated with every facet of contending with human viral disease, to managing the consequences of viral disease in organisms important to our food supply, economy, and entertainment. The...
Resource Type:: Dissertation

The conserved biology of herpesvirus latency : a study in cyprinid herpesvirus 3

Creator:: Reed, Aimee N.
Abstract:: Cyprinid herpesvirus 3 (CyHV-3), commonly known as koi herpesvirus (KHV), is a member of the Alloherpesviridae and is a deadly pathogen for koi and common carp, Cyprinus carpio. It causes severe gill necrosis and nephritis, dermal ulceration and hemorrhage, and mass mortality of up to 100% of affected fish. Fish...
Resource Type:: Dissertation

Expanding Diagnostic Assays for Pseudoloma neurophilia & Description of the Progression of Infection in Adult Zebrafish Populations

Creator:: Schuster, Corbin J.
Abstract:: Pseudoloma neurophilia is the most common pathogen reported in zebrafish (Danio rerio) research facilities and is an important threat to the zebrafish model. This microsporidian parasite can cause clinical disease, but more importantly is a causative agent of non-protocol induced variation in research. Studies utilizing infected zebrafish, could potentially confound...
Resource Type:: Dissertation
Full Text:: . George Streisgner, University of Oregon (Eisen 2020), a geneticist who studied embryo development. Now

Translation of dengue virus RNA : influence of the untranslated regions on 5´-cap dependent translation and ribosome scanning

Creator:: Chiu, Wei-Wei
Abstract:: In this thesis, I studied the translation of dengue virus RNA using a luciferase reporter gene system in Vero cells. The dengue reporter mRNA construct, which harbors 5´-terminal viral nts and 3´-terminal nts, could be translated efficiently compared to an alpha globin reporter construct. The 5´-cap structure and 3´-untranslated region...
Resource Type:: Dissertation
Full Text:: member Dr. George Rohrmann for providing helpful scientific discussion and crucial reagent for chapter

Harnessing Heterogeneity in Human Gut Microbiome Data

Creator:: Tataru, Christine
Abstract:: The focus of this thesis is to design, characterize, and apply novel computational methods and molecular systems to interrogate heterogeneous human gut microbiome-related phenomena. In Chapter 2, I design, implement, and characterize a method for embedding co-occurrence patterns derived from massive 16s amplicon datasets. I use this method to 1....
Resource Type:: Dissertation

ScholarsArchive@OSU

Cloning and biochemical characterization of the hectochlorin biosynthetic gene cluster from the marine cyanobacterium Lyngbya majuscula

Impacts of Environmental Change on a Newly-characterized Symbiosis between a Novel Bacterial Parasite, Genus Aquarickettsia, and the Coral Acropora cervicornis

Chemical and Genetic Investigations of Toxic Freshwater Cyanobacterial Blooms for Improved Monitoring and Understanding of Lake Ecology

Effects of Anthropogenic Stressors on Seagrass and Coral Microbiomes

Establishment and dynamics of methane-oxidizing microbial communities in marine sediments

Host-pathogen Interactions of Respiratory RNA Viruses and the Application of Recombinase Polymerase Amplification for Viral Diagnostics

The conserved biology of herpesvirus latency : a study in cyprinid herpesvirus 3

Expanding Diagnostic Assays for Pseudoloma neurophilia & Description of the Progression of Infection in Adult Zebrafish Populations

Translation of dengue virus RNA : influence of the untranslated regions on 5´-cap dependent translation and ribosome scanning

Harnessing Heterogeneity in Human Gut Microbiome Data

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