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Filtering by: Creator Silva, George Academic Affiliation Microbiology Subject Dengue viruses

Host-pathogen Interactions of Respiratory RNA Viruses and the Application of Recombinase Polymerase Amplification for Viral Diagnostics

Creator:

Prescott, Meagan A.

Abstract:

Humans and viral disease are inextricably intertwined. Viral disease plays an immeasurable role in human life, from the disease and economic burden associated with every facet of contending with human viral disease, to managing the consequences of viral disease in organisms important to our food supply, economy, and entertainment. The...

Resource Type:

Dissertation
Translation of dengue virus RNA : influence of the untranslated regions on 5´-cap dependent translation and ribosome scanning

Creator:

Chiu, Wei-Wei

Abstract:

In this thesis, I studied the translation of dengue virus RNA using a luciferase reporter gene system in Vero cells. The dengue reporter mRNA construct, which harbors 5´-terminal viral nts and 3´-terminal nts, could be translated efficiently compared to an alpha globin reporter construct. The 5´-cap structure and 3´-untranslated region...

Resource Type:

Dissertation

Full Text:

member Dr. George Rohrmann for providing helpful scientific discussion and crucial reagent for chapter