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Filtering by: Subject Bacterial proteins -- Denaturation Academic Affiliation Microbiology

The role of chlamydial inclusion membrane proteins in host-pathogen interaction and the development of novel methods for studying chlamydial biology

Creator:

Alzhanov, Damir T.

Abstract:

The majority of our modern understanding of bacterial pathogenesis is based on the strategy that involves screening bacterial genomes for the presence of the genes encoding pathogenic factors, and analysis of these genes via forward and reverse genetics. Chlamydiae represent a unique group of pathogenic bacteria in which it is...

Resource Type:

Dissertation

Full Text:

bacterial OmpA protein, exposed on the surface of EB (143), and heparan sulfate containing
Molecular and genetic assessment of selected antiporters and methyl-accepting chemotaxis proteins in Vibrio cholerae

Creator:

Quinn, Matthew J.

Abstract:

The pathogen Vibrio cholerae uses cations as a primary currency of virulence and environmental persistence, using gradients of those cations to move, acquire nutrients, and control virulence gene expression. An understanding of the overlapping roles of bioenergetics and chemotaxis in the virulence and environmental survival of V. cholerae issues from...

Resource Type:

Dissertation

Full Text:

mid-logarithmic phase, after 4-6 hours of culturing. Using a pH-sensitive GFP protein, cytosolic pH