Index Catalog // ScholarsArchive@OSU

Creator:: Robinson, Tanner M.
Abstract:: In a process called quorum sensing (QS), the bacterial pathogen Pseudomonas aeruginosa uses small diffusible signals to coordinate cooperative behaviors via secreted “public goods”. Under QS-dependent growth conditions, social cheaters arise with mutations in lasR, the gene for the primary QS signal receptor. These cheaters do not produce public goods....
Resource Type:: Masters Thesis
Full Text:: PA O1 las R rpo S5 rpo S: :G mR ps dR 1 ps dR 1 r po S5 0 2 4 6 8 Zo ne D is ta nc

Creator:: Neal, James T., Peterson, Tracy S., Kent, Michael L., and Guillemin, Karen
Abstract:: Infection with Helicobacter pylori is a major risk factor for the development of gastric cancer, and infection with strains carrying the virulence factor CagA significantly increases this risk. To investigate the mechanisms by which CagA promotes carcinogenesis, we generated transgenic zebrafish expressing CagA ubiquitously or in the anterior intestine. Transgenic...
Resource Type:: Article
Full Text:: telencephalon and eyes to diencephalon. Genes Dev. 15, 1427-1434. Her, G. M., Chiang, C. C. and Wu, J. L. (2004

Creator:: Rodriguez-Mari, Adriana, Wilson, Catherine, Titus, Tom A., Canestro, Cristian, BreMiller, Ruth A., Yan, Yi-Lin, Nanda, Indrajit, Johnston, Adam, Kanki, John P., Gray, Erin M., He, Xinjun, Spitsbergen, Jan, Schindler, Detlev, and Postlethwait, John H.
Abstract:: Mild mutations in BRCA2 (FANCD1) cause Fanconi anemia (FA) when homozygous, while severe mutations cause common cancers including breast, ovarian, and prostate cancers when heterozygous. Here we report a zebrafish brca2 insertional mutant that shares phenotypes with human patients and identifies a novel brca2 function in oogenesis. Experiments showed that...
Resource Type:: Article
Full Text:: ; pc, pyknotic cells; po, perinucleolar oocyte; sc, spermatocytes; sd, spermatids; sg, spermatogonia

Creator:: Dick, Linda K.
Abstract:: Contamination of recreational and shellfish waters with fecal pollution is a major water quality issue with associated economic impacts and human health risks. Reliable fecal source identification and rapid, quantitative analyses are essential components of risk assessment. Enteric bacteria that are endemic to specific hosts have a potential role as...
Resource Type:: Dissertation

Creator:: Schuster, Corbin J.
Abstract:: Pseudoloma neurophilia is the most common pathogen reported in zebrafish (Danio rerio) research facilities and is an important threat to the zebrafish model. This microsporidian parasite can cause clinical disease, but more importantly is a causative agent of non-protocol induced variation in research. Studies utilizing infected zebrafish, could potentially confound...
Resource Type:: Dissertation

Creator:: Maher, Rebecca L.
Abstract:: On coral reefs, disturbances rarely occur in isolation. Global stressors such as increasing seawater temperature often coincide with local stressors like nutrient pollution. In the face of increasing anthropogenic stress, corals can function as environmental sentinels, although little is known about how multiple stressors interact to disrupt their associated bacterial...
Resource Type:: Dissertation

Creator:: Prescott, Meagan A.
Abstract:: Humans and viral disease are inextricably intertwined. Viral disease plays an immeasurable role in human life, from the disease and economic burden associated with every facet of contending with human viral disease, to managing the consequences of viral disease in organisms important to our food supply, economy, and entertainment. The...
Resource Type:: Dissertation

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