Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Committee Member Fu, Elain Academic Affiliation Microbiology

Characterization of Mycobacterium avium subsp. hominissuis Interactions with Host Macrophages and Multinucleated Giant Cells

Creator:

Joseph, Jayanthi J.

Abstract:

To examine the macrophage response to M. avium, I compared inflammasome and cytosolic sensor expression and activation. My result demonstrated that virulent strains of M. avium (A5 and 104) suppress IL-1β production and induce IFN-β production in macrophages. M. avium mutants deficient at DNA export in the biofilm exhibited reduced...

Resource Type:

Dissertation

Full Text:

, Dr. Elain Fu, Dr. Daniel Rockey, and Dr. Martin Schuster for serving on my graduate committee