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Filtering by: Creator McNamara, Michael Remove constraint Creator: McNamara, Michael Academic Affiliation Microbiology Remove constraint Academic Affiliation: Microbiology

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  • Cooperation and conflict in Pseudomonas aeruginosa quorum sensing

    Creator:
    Wilder, Cara N.
    Abstract:
    Pseudomonas aeruginosa is an environmental bacterium as well as an opportunistic pathogen that primarily infects immunocompromised individuals, including those suffering from cystic fibrosis. The density-dependent regulation of gene expression via cell-to-cell communication, also termed quorum sensing (QS), is an important virulence determinant in this organism. Generally, P. aeruginosa uses three...
    Resource Type:
    Dissertation

  • The conserved biology of herpesvirus latency : a study in cyprinid herpesvirus 3

    Creator:
    Reed, Aimee N.
    Abstract:
    Cyprinid herpesvirus 3 (CyHV-3), commonly known as koi herpesvirus (KHV), is a member of the Alloherpesviridae and is a deadly pathogen for koi and common carp, Cyprinus carpio. It causes severe gill necrosis and nephritis, dermal ulceration and hemorrhage, and mass mortality of up to 100% of affected fish. Fish...
    Resource Type:
    Dissertation
    Full Text:
    dedication to my success: Dr. Andrew Buermeyer, Dr. Michael Kent, Dr. Malcolm Lowry, and Dr. Jerry Heidel

  • Disease models and infectious phenotypes of Mycobacterium avium subspecies paratuberculosis

    Creator:
    Everman, Jamie L.
    Abstract:
    Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne's disease, a chronic inflammatory bowel disease that affects ruminant populations worldwide. The characteristic stages of the disease make diagnosis difficult, resulting in silent transmission among animals in a herd for years before proper detection of the infection. The extensive...
    Resource Type:
    Dissertation
    Full Text:
    , Rashmi Gupta, Jessica Chinison, Michael McNamara, and Laura Hauck, your suggestions, brainstorming

  • Characterization of microaggregate formation by Mycobacterium avium subspecies hominissuis

    Creator:
    Babrak, Lmar
    Abstract:
    Mycobacterium avium subsp hominissuis (MAH) is an opportunistic environmental pathogen that causes respiratory and gastrointestinal illness in immunocompromised persons such as those with chronic respiratory diseases or AIDs, respectively. In recent years, there has been a significant increase in the incidence of nontuberculous mycobacterial (NTM) lung infections, including in cystic...
    Resource Type:
    Dissertation
    Full Text:
    , Jessica Chinison, Dr. Michael McNamara, Val Elias, Laura Hauk, and Mathew Lewis. To all the students I

  • Further Understanding Mycobacterial Biofilms and Their Interaction with the Host

    Creator:
    Rose, Sasha J.
    Abstract:
    Respiratory infections caused by nontuberculous mycobacteria (NTM), especially Mycobacterium avium, can lead to progressive, recurrent disease that is refractory to therapy. Bacterial biofilms are intrinsically resistant to a variety of stressors and pressures, including host killing mechanisms and antibiotic therapy. Though it is becoming increasingly evident that NTM biofilms are...
    Resource Type:
    Dissertation
    Full Text:
    to Michael McNamara, who trained me initially as an undergrad and both taught me essential

  • Ruminal Biodegradation of Heterocyclic Toxic Compounds

    Creator:
    Tanaree, Dan D.
    Abstract:
    Cyclic nitramines are a class of compounds that include most of the commonly used explosives today. These are among the most common toxicants released into the environment as a result of human activity, generated on military ranges, battlefields, and production sites. Of these, hexahydro-1,3,5-trinitro-1,3,5- triazine (RDX) is of particular interest,...
    Resource Type:
    Dissertation
    Full Text:
    (McNamara et al. 2015). Cellulose is extremely resistant to damage or degradation, and most breakdown in