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Filtering by: Creator Mendez, Christopher Academic Affiliation Microbiology

Characterizing the Accuracy of Phylogenetic Analyses that Leverage 16S rRNA Sequencing Data

Creator:

Humphreys, Ian R.

Abstract:

Investigations of 16S rRNA gene sequences hallmark modern microbiology. These sequences provide culture-independent insight into the abundance and distribution of microbiota and serve as a principle resource through which microbial community diversity is measured. Consequently, researchers rely on 16S gene sequences to test hypotheses rooted in ecology, evolution, and disease....

Resource Type:

Masters Thesis

Full Text:

enjoyed working in. I owe a special thanks to Dr. Christopher Gaulke for his technical assistance
Host-pathogen Interactions of Respiratory RNA Viruses and the Application of Recombinase Polymerase Amplification for Viral Diagnostics

Creator:

Prescott, Meagan A.

Abstract:

Humans and viral disease are inextricably intertwined. Viral disease plays an immeasurable role in human life, from the disease and economic burden associated with every facet of contending with human viral disease, to managing the consequences of viral disease in organisms important to our food supply, economy, and entertainment. The...

Resource Type:

Dissertation
Harnessing Heterogeneity in Human Gut Microbiome Data

Creator:

Tataru, Christine

Abstract:

The focus of this thesis is to design, characterize, and apply novel computational methods and molecular systems to interrogate heterogeneous human gut microbiome-related phenomena. In Chapter 2, I design, implement, and characterize a method for embedding co-occurrence patterns derived from massive 16s amplicon datasets. I use this method to 1....

Resource Type:

Dissertation