Index Catalog // ScholarsArchive@OSU

Expanding Diagnostic Assays for Pseudoloma neurophilia & Description of the Progression of Infection in Adult Zebrafish Populations

Creator:: Schuster, Corbin J.
Abstract:: Pseudoloma neurophilia is the most common pathogen reported in zebrafish (Danio rerio) research facilities and is an important threat to the zebrafish model. This microsporidian parasite can cause clinical disease, but more importantly is a causative agent of non-protocol induced variation in research. Studies utilizing infected zebrafish, could potentially confound...
Resource Type:: Dissertation
Full Text:: infection. Using water samples from the Zebrafish International Resource Center, Eugene Oregon, I also

Controlling Important Pathogens in Zebrafish (Danio rerio) : Assessing Cryopreservation Survival of Bacteria and Parasites and Clinical Sensitivity of Mycobacterial qPCR Assays

Creator:: Norris, Lauren J.
Abstract:: Zebrafish (Danio rerio) are one of the most commonly used animal models in biomedical research. Zebrafish resource facilities, like the Zebrafish International Resource Center (ZIRC) in Eugene, Oregon, are the main providers and keepers of numerous zebrafish wild-type, mutant, and transgenic lines. Although ZIRC maintains live zebrafish at various life...
Resource Type:: Masters Thesis
Full Text:: ) in Eugene, Oregon, are the main providers and keepers of numerous zebrafish wild-type, mutant, and

Transgenic expression of Walleye dermal sarcoma virus rv-cyclin gene in zebrafish and its protective effect on liver-tumor development after carcinogen treatment

Creator:: Zhan, Huiqing, Spitsbergen, Jan, Qing, Wei, Wu, Yi Lian, Paul, Thomas A., Casey, James W., and Gong, Zhiyuan
Abstract:: A retrovirus homologue gene of cellular cyclin D₁, walleye dermal sarcoma virus rv-cyclin gene (orf A or rv-cyclin), was expressed in the livers of zebrafish under the control of liver fatty-acid binding protein (lfabp) promoter. To prevent possible fatality caused by over-expression of the oncogene, the GAL4/UAS system was used...
Resource Type:: Article
Full Text:: these effects (Zhang and Martineau, 1999). However, BLAST search found that the N-terminal of rv

Chemical and Genetic Investigations of Toxic Freshwater Cyanobacterial Blooms for Improved Monitoring and Understanding of Lake Ecology

Creator:: Collart, Lindsay P.
Abstract:: Toxin production by cyanobacterial harmful algal blooms (cyanoHABs) in freshwater systems has lasting ecological and human impacts. Nutrients, light availability, hydrology, and microbial community composition impact the frequency and intensity of toxic cyanoHABs. Climate change will exacerbate toxic cyanoHABs, making real time and predictive monitoring a vital tool for managing...
Resource Type:: Dissertation
Full Text:: systems and accumulating in soils, fish, produce, bivalves, and crustaceans (Yang, Kong, and Zhang 2016

Intestinal hyperplasia and neoplasms in zebrafish (Danio rerio)

Creator:: Paquette, Colleen Elizabeth
Abstract:: Zebrafish (Danio rerio) have become an increasingly important model organism for cancer research. There are several cancer models in which neoplasms are induced chemically or genetically. However, spontaneous (unknown etiology) neoplasms are rather common in zebrafish, particularly in older fish. For over a decade, spontaneous intestinal neoplasia and preneoplastic intestinal...
Resource Type:: Masters Thesis
Full Text:: , Eugene, Oregon. 5University of Oregon Zebrafish Facility, Institute of Neuroscience, University of

The conserved biology of herpesvirus latency : a study in cyprinid herpesvirus 3

Creator:: Reed, Aimee N.
Abstract:: Cyprinid herpesvirus 3 (CyHV-3), commonly known as koi herpesvirus (KHV), is a member of the Alloherpesviridae and is a deadly pathogen for koi and common carp, Cyprinus carpio. It causes severe gill necrosis and nephritis, dermal ulceration and hemorrhage, and mass mortality of up to 100% of affected fish. Fish...
Resource Type:: Dissertation

H. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish model

Creator:: Neal, James T., Peterson, Tracy S., Kent, Michael L., and Guillemin, Karen
Abstract:: Infection with Helicobacter pylori is a major risk factor for the development of gastric cancer, and infection with strains carrying the virulence factor CagA significantly increases this risk. To investigate the mechanisms by which CagA promotes carcinogenesis, we generated transgenic zebrafish expressing CagA ubiquitously or in the anterior intestine. Transgenic...
Resource Type:: Article
Full Text:: 1Institute of Molecular Biology, University of Oregon, Eugene, OR 97403, USA 2Department of Microbiology

Assessing disease impacts of hatcheries on downstream salmonids in the Willamette River Basin, Oregon

Creator:: Jakaitis, Michelle
Abstract:: Hatcheries are often perceived as a source of pathogen amplification, potentially increasing disease risk to free-ranging populations; at the same time, free-ranging fishes may introduce pathogens into hatcheries through untreated water sources. Many pathogens exist naturally within the environment (with the exception of introduced pathogens) and the presence of a...
Resource Type:: Masters Thesis
Full Text:: ) or PCR combined with a DNA probe (Zhang and Congleton 1994; Batts and Winton 1989; O’Brien et al

Harnessing Heterogeneity in Human Gut Microbiome Data

Creator:: Tataru, Christine
Abstract:: The focus of this thesis is to design, characterize, and apply novel computational methods and molecular systems to interrogate heterogeneous human gut microbiome-related phenomena. In Chapter 2, I design, implement, and characterize a method for embedding co-occurrence patterns derived from massive 16s amplicon datasets. I use this method to 1....
Resource Type:: Dissertation

Single-Cell Genomics of Uncultivated Marine Bacteria

Creator:: Landry, Zachary
Abstract:: Historically, the difficulty of obtaining pure cultures of abundant marine microbial plankton has an obstacle to reconstructing the underlying mechanisms of biogeochemistry in the ocean. While a number of dominant marine species from the ocean surface have been cultured, the dominant microbial plankton of the dark ocean proved far more...
Resource Type:: Dissertation
Full Text:: and could be used as template for whole-genome shotgun sequencing (Lasken, 2007; Zhang et al., 2006

ScholarsArchive@OSU

Expanding Diagnostic Assays for Pseudoloma neurophilia & Description of the Progression of Infection in Adult Zebrafish Populations

Controlling Important Pathogens in Zebrafish (Danio rerio) : Assessing Cryopreservation Survival of Bacteria and Parasites and Clinical Sensitivity of Mycobacterial qPCR Assays

Transgenic expression of Walleye dermal sarcoma virus rv-cyclin gene in zebrafish and its protective effect on liver-tumor development after carcinogen treatment

Chemical and Genetic Investigations of Toxic Freshwater Cyanobacterial Blooms for Improved Monitoring and Understanding of Lake Ecology

Intestinal hyperplasia and neoplasms in zebrafish (Danio rerio)

The conserved biology of herpesvirus latency : a study in cyprinid herpesvirus 3

H. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish model

Assessing disease impacts of hatcheries on downstream salmonids in the Willamette River Basin, Oregon

Harnessing Heterogeneity in Human Gut Microbiome Data

Single-Cell Genomics of Uncultivated Marine Bacteria

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