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Filtering by: Academic Affiliation Pharmacology and Toxicology Advisor Larson, Robert E. Date issued sim 1974-07-18

A comparison of the effect of pH change upon the uptake of 5-fluorouracil into rat liver and Walker 256 carcinosarcoma slices

Creator:

Hult, Richard Lee

Abstract:

An enhancement of the therapeutic effect and/or a reduction in the toxicity have been shown by a variety of antineoplastic compounds when glucose is added to the treatment schedule. A possible explanation for this involves a selective change in intracellular pH of the tumor tissue initiating a greater uptake of...

Resource Type:

Masters Thesis