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Filtering by: Subject Microsomes -- Effect of chemicals on Remove constraint Subject: Microsomes -- Effect of chemicals on Academic Affiliation School of Biological and Population Health Sciences Remove constraint Academic Affiliation: School of Biological and Population Health Sciences

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  • In Utero Exposure to Arsenic and Mercury : Epigenome-Wide Associations and Newborn Health Outcomes

    Creator:
    Cardenas, Andres
    Abstract:
    Mercury and arsenic are known developmental toxicants and environmental exposures are ubiquitous worldwide from natural and anthropogenic sources. Prenatal exposure to both contaminants are independently associated with adverse perinatal health outcomes and latent disease risk that could be in part mediated by epigenetic reprogramming events. Fetal programming events involving DNA...
    Resource Type:
    Dissertation
    Full Text:
    methylation in different biological human tissues. Particularly, the effect of arsenic exposure on

  • Environmental Mixtures and Selected Health Outcomes in the US Population

    Creator:
    Przybyla, Jennifer
    Abstract:
    The human health effects of exposure to numerous single environmental contaminants have been well characterized. Yet, biomonitoring studies have detected multiple environmental chemicals in humans, highlighting the need to investigate the health effects of exposure to multiple environmental chemicals. Environmental data is highly complex, therefore current methods of defining environmental...
    Resource Type:
    Dissertation
    Full Text:
    ......................................................................... 8 Evaluation of chemical mixtures on human health

  • Embryonic and Larval Zebrafish Bioassays for Biomedical Research : The Larval Photomotor Response Screening Assay and Phenotype

    Creator:
    Fisher, Joseph A.
    Abstract:
    Laboratories around the world are using the zebrafish model for biomedical research and conducting investigations using morphological, physiological, behavioral, and genomic endpoints. All assays provide information, but physiological and behavioral endpoints or phenotypes are a fast way to understand how an animal is responding to its environment. We investigate the...
    Resource Type:
    Dissertation
    Full Text:
    the burden-of-proof on the chemical supplier to demonstrate substance health and safety, while in