Background: According to the National Mental Health Survey (NMHS), the treatment gap of any mental disorder in India among the general population was reported to be as high as 83% (R. S. Murthy, 2017). There is insufficient evidence currently describing the treatment gap among the child and adolescent population. Given...
Alcohol is a widely consumed, nonessential, bioactive nutrient with end-organ effects on the skeleton. Moderate levels of alcohol consumption are generally associated with increased bone mineral density (BMD), whereas higher intake levels result in reduced bone formation, bone loss, and increased risk for osteoporotic fracture. Given the negative impact of...
Nonalcoholic fatty liver disease (NAFLD) is characterized by an accumulation of neutral lipids in the form of triglycerides and cholesterol esters accounting for >5% of liver weight. Excess neutral lipids accumulate in large lipid droplets, i.e., macrosteatosis, displacing the nucleus of cells. Current theory suggests neutral lipid accumulation is the...
The importance of physical activity is well documented (Haskell et al., 2009a; McReynolds & Rossen, 2004; Steinbeck, 2001). Despite physical activity’s benefits, many individuals are not meeting current weekly physical activity guidelines recommending ≥ 150 minutes of moderate or ≥ 75 minutes of vigorous aerobic physical activity and 2 or...
Adapted physical activity and education (APA/APE) service-learning has received considerable attention as a training tool to prepare undergraduate students, including preservice physical education teachers, to work with people with disabilities (Hodge, 1998; Rowe & Stutts, 1987; Taliaferro et al., 2015). Much of this research focuses on demonstrating the effects of...
Obesity and metabolic syndrome (MetS) affect over 1.9 billion adults and 12.7 million youth in the US. If all of today’s obese American youth become obese adults, the total societal costs over their lifetime may exceed $1.1 trillion. We show that feeding rodents a high-fat diet supplemented with xanthohumol (XN)...
Marginalized groups in the United States are often diagnosed with hypertension at younger ages, contributing to their excess burden of cardiovascular disease. These disparities in blood pressure control do not appear to be fully accounted for by individual risk factors, such as health behaviors or genetic differences. Experiences of discrimination...
Introduction: For people with bleeding disorders pain is often a daily challenge. Despite many advancements to the standard of care in recent decades, including more effective treatments, and more effective medication schedules, pain remains highly prevalent in people with bleeding disorders: existing pain treatment practices have not adequately addressed pain...
Quantitative measurement of the urban-rural continuum for examination of U.S. rural health disparities is a relatively new research area, where only a handful of studies have investigated health disparities using quantitative rural measures and even fewer have attempted to integrate health variables within said measures. Most U.S. rural health disparity...
Premature birth interrupts the typical development of the human fetus, leaving the infant born with underdeveloped gastrointestinal and immune systems. Preterm infants have reduced stomach acidity, reduced digestive protease activity, more permeable intestinal membranes, impaired innate and adaptive immune response, and poor microbiome development. Due to these factors, preterm infants...