Index Catalog // ScholarsArchive@OSU

Creator:: Pike, Daniel B.
Abstract:: Biocompatible hydrogels composed of covalently crosslinked, chemically modified hyaluronan (HA), gelatin (Gtn), and heparin (Hp) were synthesized for controlled release of human vascular endothelial growth factor (VEGF) or basic fibroblast growth factor (bFGF). We hypothesized that inclusion of small quantities of heparin in these gels would result in regulated growth...
Resource Type:: Masters Thesis

Creator:: Lusianti, Ratih E.
Abstract:: Cryoprotectants (CPAs) such as glycerol and dimethyl sulfoxide (DMSO) are commonly used during cryopreservation of cell based therapeutics. Although these additives are beneficial during freezing, it is often desirable to remove them before infusion into a patient. Currently, the most common method for CPA removal is by centrifugation. This method...
Resource Type:: Masters Thesis

Creator:: Wu, Jianyong
Abstract:: The adduction of proteins and other biomolecules by electrophilic lipid peroxidation products such as 4-hydroxy-2-nonenal (HNE), 4-oxo-2-nonenal (ONE), malondialdehyde (MDA) or acrolein (ACR) is thought to be an initiating and/or propagating factor in the pathophysiology of several diseases such as atherosclerosis, diabetes, Alzheimer's, Parkinson's and other age-related disorders. The identification...
Resource Type:: Dissertation

Creator:: Coblyn, Matthew Y.
Abstract:: There are approximately 2.2 million cases of End-stage Renal Disease (ESRD) worldwide and current hemodialysis treatment is costly and ultimately insufficient compared to kidney transplantation. There is a strong need to arrive at a better solution for treating ESRD. Microchannel-based hemodialysis is one proposed option, already shown to have improved...
Resource Type:: Dissertation

Creator:: Fry Davidson, Allyson
Abstract:: Cryopreservation of adherent cells may be advantageous for cell types that are difficult to preserve in suspension or when it is necessary to preserve characteristics of the adherent cultured cells. Vitrification is a promising procedure for the preservation of adherent cells that prevents ice crystal formation and the resulting dissociation...
Resource Type:: Dissertation

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