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Filtering by: Creator Ezell, Andrew W. Remove constraint Creator: Ezell, Andrew W. Degree Name Honors Bachelor of Science (H.B.S.) Remove constraint Degree Name: Honors Bachelor of Science (H.B.S.)

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  • Investigating the Role of the MutLα Endonuclease

    Creator:
    Mankaney, Gautam Naresh
    Abstract:
    Lynch individuals have a predisposition to developing colorectal and other cancers due to inherited defects in their mismatch repair (MMR) system. Although mutations in MMR have been directly implicated in Lynch Syndrome, the precise mechanism(s) of MMR functions have yet to be elucidated. One essential complex, MutL (a dimer of...
    Resource Type:
    Honors College Thesis
    Full Text:
    . Abstract Approved:________________________________________________________ Andrew Buermeyer Lynch

  • A Novel Approach to the Biochemical Analysis of Variants in the Essential DNA Mismatch Repair Protein MLH1

    Creator:
    Nguyen, Andrew
    Abstract:
    Genomic integrity is crucial for the viability and function of a cell. One key pathway that acts to maintain genomic integrity is DNA mismatch repair (MMR). MMR acts to correct base pair mismatches hat have escaped proofreading during DNA replication. The process of MMR is dependent on the protein heterodimer...
    Resource Type:
    Honors College Thesis
    Full Text:
    Andrew Nguyen Honors Thesis AN ABSTRACT OF THE

  • Effect of Fire Severity on Forest Development in a Mature Douglas-fir Forest in Western Oregon

    Creator:
    Hidzick, Maxim S.
    Abstract:
    Wildfires can create alternative pathways for forest development, and wildfires have expanded in size, frequency, intensity, and severity across the western United States. The purpose of this paper is to compare forest development of a mature Douglas-fir forest in western Oregon across fire severities. Postburn field measurements were collected in...
    Resource Type:
    Honors College Thesis
    Full Text:
    Oregon. Abstract approved:_____________________________________________________ Andrew

  • Pathogenic Mechanisms of Cancer Causing hMLH1 Mutations

    Creator:
    O'Donnell, Edmond Francis
    Abstract:
    DNA mismatch repair (MMR) is an evolutionary conserved process that functions to maintain genomic integrity through the correction of mismatches that have escaped proofreading. Mutations in the MMR gene Mlh1 are associated with approximately 50% of all cases of Lynch syndrome, a hereditary predisposition to colorectal cancer, through varying and...
    Resource Type:
    Honors College Thesis
    Full Text:
    . Abstract Approved: Andrew Buermeyer DNA mismatch repair (MMR) is an evolutionary conserved process that

  • DNA Mismatch Repair-Dependent Suppression of Genotoxicity of Benzo[a]pyrene Diol Epoxide

    Creator:
    Kernan, Casey P.
    Abstract:
    DNA mismatch repair (MMR) plays an important role in preserving genomic stability and reducing cancer risk. Environmental exposures to polycyclic aromatic hydrocarbons (PAHs) are believed to contribute significantly to carcinogenesis. PAHs are found in food, air, water and soil and upon bioactivation can form diol epoxides which are electrophilic in...
    Resource Type:
    Honors College Thesis
    Full Text:
    Andrew Buermeyer DNA mismatch repair (MMR) plays an important role in

  • Creating Test Baking Methods Specifically for Whole-Wheat Sourdough Breads, In the Context of Local Grain Economies

    Creator:
    Jansen, Victoria E.
    Abstract:
    Recently local grains have become an area of economic growth. Local grain products, including whole-wheat and sourdough products, are increasingly in demand for their health benefits, unique flavor profiles, and association with local food movements. These local grain economies are beginning to boom, but they lack the technical aid that...
    Resource Type:
    Honors College Thesis
    Full Text:
    Andrew Ross Recently local grains have become an area of economic growth. Local grain products

  • Lamb growth and pasture production in agrivoltaic production system

    Creator:
    Andrew, Alyssa C.
    Abstract:
    Grasslands and croplands located in temperate agro-ecologies are ranked to be the best places to install solar panels for maximum energy production. Therefore, agrivoltaic systems (agricultural production under solar panels) are designed to mutually benefit solar energy and agricultural production in the same location for dual-use of land. However, both...
    Resource Type:
    Honors College Thesis
    Full Text:
    production system by Alyssa Andrew A THESIS submitted to Oregon State

  • Design of a Radioisotope Powered Cubesat

    Creator:
    McConnell, Brice David
    Abstract:
    Miniature satellites called cubesats have been gaining increasing popularity in both academic and private spaceflight ventures. NASA's Jet Propulsion Laboratory has recently been accepting design proposals for a cubesat mission to Europa, where solar and battery power would be inadequate power sources. In this thesis, a radioisotope powered cubesat was...
    Resource Type:
    Honors College Thesis
    Full Text:
    :_____________________________________________________ Andrew Klein Miniature satellites called cubesats have been gaining increasing popularity in

  • Partial Characterization of the Danio rerio and Xenopus tropicalis MT-­‐Ox Enzyme Involved in Gadusol Biosynthesis

    Creator:
    Roemelt, Taylor
    Abstract:
    Ultraviolet (UV)-protective compounds, such as mycosporine-like amino acids (MAA) are critical for the survival of marine organisms exposed to high-solar radiation. A chemically similar compound, gadusol, was discovered in eggs of the atlantic cod in 1980, and was originally thought to be derived from MAAs that had been ingested. However,...
    Resource Type:
    Honors College Thesis
    Full Text:
    : ______________________________________________________ P.  Andrew  Karplus       Ultraviolet  (UV)-­‐protective  compounds,  such

  • The Crystal Structure of the Potential Drug Target Mycoplasma pneumoniae Glycerol 3-Phosphate Oxidase

    Creator:
    Palioca, Callia K.
    Abstract:
    Mycoplasma pneumoniae is the primary cause of community-acquired pneumonias, including what is commonly known as walking pneumonia. This disease affects people from all demographics, but especially children and older adults. Outbreaks are a significant public health concern and work to develop new pharmacological agents is currently being researched. How M....
    Resource Type:
    Honors College Thesis
    Full Text:
    P. Andrew Karplus Mycoplasma pneumoniae is the primary cause of community-acquired pneumonias