Index Catalog // ScholarsArchive@OSU

Toad Populations Decreasing in South Korea

Creator:: Chung, Yun Soo
Abstract:: Massive die-offs of Bufo bufo gargarizans were observed in May 2008 in Mangwal Gee, Korea. To find out the causes for this disaster several different elements were examined: pH, total nitrogen, dissolved oxygen (DO), and dissolved heavy metal, suspension, introduced species, habitat change, disease, temperature changes, and precipitation and humidity....
Resource Type:: Honors College Thesis
Full Text:: approved : Andrew Blaustein

The ecology of disease and anthropogenic stressors in amphibians

Creator:: French, Kellie M.
Abstract:: We proposed to test the hypothesis that ecologically relevant concentrations of pesticide mixtures will increase susceptibility of metamorphic amphibians to a fungal pathogen known as Batrachochytrium dendrobatidis, or Bd. Bd has received considerable attention as one of the causes of declining amphibian populations. We hypothesized that exposure to the contaminants...
Resource Type:: Honors College Thesis

Diversity and distribution of bacterial symbionts in Vesicomyid clams along the Cascadia Margin

Creator:: Robinson, Hannah R.
Abstract:: Deep-sea chemosynthetic ecosystems remain a frontier in marine science. Essential to their role in the ocean ecosystem are endosymbiotic bacteria which support larger megafauna, including the widespread symbiont-bearing Vesicomyid clams. The diversity and characteristics of these symbionts in these clams is only just beginning to be understood with technological advances...
Resource Type:: Honors College Thesis
Full Text:: approved:_____________________________________________________ Andrew Thurber Deep-sea

Investigating the Role of the MutLα Endonuclease

Creator:: Mankaney, Gautam Naresh
Abstract:: Lynch individuals have a predisposition to developing colorectal and other cancers due to inherited defects in their mismatch repair (MMR) system. Although mutations in MMR have been directly implicated in Lynch Syndrome, the precise mechanism(s) of MMR functions have yet to be elucidated. One essential complex, MutL (a dimer of...
Resource Type:: Honors College Thesis
Full Text:: . Abstract Approved:________________________________________________________ Andrew Buermeyer Lynch

A Novel Approach to the Biochemical Analysis of Variants in the Essential DNA Mismatch Repair Protein MLH1

Creator:: Nguyen, Andrew
Abstract:: Genomic integrity is crucial for the viability and function of a cell. One key pathway that acts to maintain genomic integrity is DNA mismatch repair (MMR). MMR acts to correct base pair mismatches hat have escaped proofreading during DNA replication. The process of MMR is dependent on the protein heterodimer...
Resource Type:: Honors College Thesis
Full Text:: Andrew Nguyen Honors Thesis AN ABSTRACT OF THE

Pathogenic Mechanisms of Cancer Causing hMLH1 Mutations

Creator:: O'Donnell, Edmond Francis
Abstract:: DNA mismatch repair (MMR) is an evolutionary conserved process that functions to maintain genomic integrity through the correction of mismatches that have escaped proofreading. Mutations in the MMR gene Mlh1 are associated with approximately 50% of all cases of Lynch syndrome, a hereditary predisposition to colorectal cancer, through varying and...
Resource Type:: Honors College Thesis
Full Text:: . Abstract Approved: Andrew Buermeyer DNA mismatch repair (MMR) is an evolutionary conserved process that

Mismatch Repair-Dependent Cellular Responses to Polycyclic Aromatic Hydrocarbons: An Investigation of Research Methods and Materials

Creator:: Wickramanayake, Anneka
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are carcinogenic chemical compounds found in the environment, largely as a result of partial combustion of organic compounds. PAHs are present in the atmosphere in populated cities worldwide. Because of the health risks they create, PAHs are a global health concern. PAHs are introduced into the...
Resource Type:: Honors College Thesis
Full Text:: :____________________________________________________ Andrew Buermeyer Polycyclic aromatic hydrocarbons (PAHs) are carcinogenic chemical

Creating Test Baking Methods Specifically for Whole-Wheat Sourdough Breads, In the Context of Local Grain Economies

Creator:: Jansen, Victoria E.
Abstract:: Recently local grains have become an area of economic growth. Local grain products, including whole-wheat and sourdough products, are increasingly in demand for their health benefits, unique flavor profiles, and association with local food movements. These local grain economies are beginning to boom, but they lack the technical aid that...
Resource Type:: Honors College Thesis
Full Text:: Andrew Ross Recently local grains have become an area of economic growth. Local grain products

Effect of Fire Severity on Forest Development in a Mature Douglas-fir Forest in Western Oregon

Creator:: Hidzick, Maxim S.
Abstract:: Wildfires can create alternative pathways for forest development, and wildfires have expanded in size, frequency, intensity, and severity across the western United States. The purpose of this paper is to compare forest development of a mature Douglas-fir forest in western Oregon across fire severities. Postburn field measurements were collected in...
Resource Type:: Honors College Thesis
Full Text:: Oregon. Abstract approved:_____________________________________________________ Andrew

DNA Mismatch Repair-Dependent Suppression of Genotoxicity of Benzo[a]pyrene Diol Epoxide

Creator:: Kernan, Casey P.
Abstract:: DNA mismatch repair (MMR) plays an important role in preserving genomic stability and reducing cancer risk. Environmental exposures to polycyclic aromatic hydrocarbons (PAHs) are believed to contribute significantly to carcinogenesis. PAHs are found in food, air, water and soil and upon bioactivation can form diol epoxides which are electrophilic in...
Resource Type:: Honors College Thesis
Full Text:: Andrew Buermeyer DNA mismatch repair (MMR) plays an important role in

ScholarsArchive@OSU

Toad Populations Decreasing in South Korea

The ecology of disease and anthropogenic stressors in amphibians

Diversity and distribution of bacterial symbionts in Vesicomyid clams along the Cascadia Margin

Investigating the Role of the MutLα Endonuclease

A Novel Approach to the Biochemical Analysis of Variants in the Essential DNA Mismatch Repair Protein MLH1

Pathogenic Mechanisms of Cancer Causing hMLH1 Mutations

Mismatch Repair-Dependent Cellular Responses to Polycyclic Aromatic Hydrocarbons: An Investigation of Research Methods and Materials

Creating Test Baking Methods Specifically for Whole-Wheat Sourdough Breads, In the Context of Local Grain Economies

Effect of Fire Severity on Forest Development in a Mature Douglas-fir Forest in Western Oregon

DNA Mismatch Repair-Dependent Suppression of Genotoxicity of Benzo[a]pyrene Diol Epoxide

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