The dissertation focuses on the engineering of light-matter interaction using plasmonic nanoparticles and metamaterials to achieve enhanced luminescence and based on which to improve the performance of biosensing and light-emitting technologies. We designed and fabricated a spectrum of nanostructures to exhibit particular dispersion relations capable of controlling the spontaneous emission...
An innovative silver nano-dimple arrays (Ag DAs)-integrated microfluidic device was developed to achieve highly sensitive fluorescence-based nucleic acid detection. The Ag DAs were utilized to produce surface plasmon resonance (SPR) for strong fluorescence enhancement. We systematically investigated the plasmon-enhanced fluorescence by controlling the nanostructure dimension of the Ag DA substrate....
We demonstrated a low-cost and high-sensitivity DNA detection method using quantum dot-fullerene based molecular beacons (MBs) and magnetic nanoparticles. The MB tethered magnetic nanoparticles can be well dispersed in analytes for efficient DNA capture and concentrated by an external magnetic field for enhanced fluorescence signal detection. The detection requires only...
Vibrio parahaemolyticus is a seafood-borne pathogen that can cause gastroenteritis in humans. This study investigated the effectiveness of refrigerated seawater (5°C) depuration on reducing V. parahaemolyticus in raw Pacific oysters (Crassostrea gigas). Raw Pacific oysters were inoculated with a mixed culture of five clinical strains of V. parahaemolyticus and depurated...
The thesis focuses on the development of a novel printed resistive humidity sensor and integrated flexible electronics for an RFID-enabled humidity sensing platform. We explored a hybrid nanocomposite material for humidity sensing consisting of carbon nanomaterials, conductive polymer and cellulose polymer that undergoes resistance change in response to humidity change....
Rapid and sensitive detection of stress hormones, such as cortisol and dehydroepiandrosterone (DHEA), can benefit the diagnosis of diseases related to adrenal gland disorders, post-traumatic stress disorders, chronic fatigue syndrome, and more. Stress hormones fluctuate in a circadian rhythm, the highest in the early morning and the lowest at night;...
We demonstrated a sensitive biosensor based on plasmonic metal composite nanostructures. The device can be fabricated and duplicated with ease using a novel nanoprinting technology which allows precise transfer of metal nanostructures without complicated lithography processes. The design featured by its unique material composition and sub-wavelength structures maximizes the exposure...
It is reported that the axial mode separation of a semiconductor
laser can be computed from the reflectance spectrum of a narrow
spectral range near the lasing frequency. The Kramers-Kronig dispersion
relation is used in this computation.
GaAs semiconductor laser is taken as an example. The computed
values of the...
Distribution of Vibrio parahaemolyticus in Oregon and Washington oystergrowing areas was studied between November 2002 and October 2003. V. parahaemolyticus was detected in 14.3% of oyster, 23.0% of seawater, and 44.4% of sediment samples with very low levels (≤7.4 MPN/g) of pathogenic strains being detected in oysters. Occurrence of V....
Scombroid poisoning, caused by histamine intoxication, is one of the most prevalent illnesses associated with seafood consumption in the United States. The illness is usually accompanied with a variety of symptoms, such as rash, nausea, diarrhea, flushing, sweating, and headache. Incidence of scombroid poisoning has been consistently reported in the...
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Yi-Cheng Su
Scombroid poisoning, caused by histamine intoxication, is one of the most