Graphical methods for displaying uncertainty are often the most concise and informative way to communicate abstract concepts. Presentation methods currently in use for the display and interpretation of scientific uncertainty are reviewed. Numerous subjective and objective uncertainty display methods are presented, including qualitative assessments, node and arrow diagrams, standard statistical...
OBJECTIVE: To evaluate the effectiveness of a 3-month treadmill desk intervention in eliciting changes in physical activity and sedentary behavior among overweight/obese office workers. METHODS: A randomized controlled trial was conducted among overweight/obese office workers (n=41; mean age = 40.1 ± 10.1 years) at a private workplace. Participants were randomly...
Background—The effect of intensive blood pressure (BP) lowering on kidney function among individuals with established cerebrovascular disease and preserved estimated glomerular filtration rate (eGFR) is not established.
Methods and Results—Among 2610 participants randomized to a lower (<130 mm Hg) versus higher (130–149 mm Hg) systolic BP target with repeated measures...
International immersion experiences do not, in themselves, provide students with the opportunity to develop cultural competence. However, using an anthropological lens to educate students allows them to learn how to negotiate cultural differences by removing their own cultural filters and seeing events through the eyes of those who are culturally...
A radioactive particulate release experiment to produce a near-field ground deposition representative of small-scale venting from an underground nuclear test was conducted to gather data in support of treaty capability development activities. For this experiment, aCO₂‐driven “air cannon” was used to inject ¹⁴⁰La, a radioisotope of lanthanum with 1.7‐d half-life...
CONTEXT: In older adults with multiple conditions, medications may not impart the same benefits seen in patients who are younger, or without multi-morbidity. Furthermore, medications given for one condition may adversely affect other outcomes. Beta-blocker (β-Blocker) use with coexisting cardiovascular disease (CVD) and chronic obstructive pulmonary disease (COPD) is such...
Objective: To examine the pricing trajectories in the United States of disease-modifying therapies (DMT) for multiple sclerosis (MS) over the last 20 years and assess the influences on rising prices.
Methods: We estimated the trend in annual drug costs for 9 DMTs using published drug pricing data from 1993 to...
BACKGROUND: In the prenatal period, women can have sustained contact with nurses and other clinicians, forming relationships that are likely to be health enhancing both for the woman and her unborn child. Yet first trimester care use in Oregon dropped noticeably over the past decade. In comparison with Washington State,...
OBJECTIVE: Pharmacokinetic interactions exist between combined
oral contraceptives and protease inhibitors (PI). However, such
information is lacking for progestin-only oral contraception. We
sought to define the steady-state pharmacokinetic interaction between
norethindrone (NET) and PI in HIV-infected women.
METHODS AND DESIGN: We conducted an open-label, prospective,
nonrandomized trial to characterize the...
Acid deposition and repeated biomass harvest have decreased
soil calcium (Ca) availability in many temperate forests worldwide, yet
existing methods for assessing available soil Ca do not fully characterize
soil Ca forms. To account for discrepancies in ecosystem Ca budgets, it
has been hypothesized that the highly insoluble biomineral Ca...
