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Filtering by: Committee Member Griffith, Stephen M. Remove constraint Committee Member: Griffith, Stephen M. Advisor Alani, Adam W. G. Remove constraint Advisor: Alani, Adam W. G.

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  • Nanomedicine Drug Delivery for the Treatment of Lymphatically Metastasizing Cancers

    Creator:
    Cote, Brianna M.
    Abstract:
    Nearly 80% of solid tumors, such as melanoma, metastasize via the lymphatic system. The most common form of melanoma is BRAF-mutant melanoma, and additional mutations, such as a PTEN mutation in the PI3K pathway, is required for metastases to occur. Standard therapy includes treatment with small molecules dabrafenib (DAB) and...
    Resource Type:
    Dissertation
    Full Text:
    THE DISSERTATION OF Brianna M. Cote for the degree of Doctor of Philosophy in Pharmaceutical