Index Catalog // ScholarsArchive@OSU

Investigating the basis of substrate specificity in butane monooxygenase and chlorinated ethene toxicity in Pseudomonas butanovora

Creator:: Halsey, Kimberly H.
Abstract:: Pseudomonas butanovora, Mycobacterium vaccae, and Nocardioides sp. CF8 utilize distinctly different butane monooxygenases (BMOs) to initiate degradation of recalcitrant chlorinated ethenes (CEs) that pollute aquifers and soils. BMO-dependent degradation of CEs such as trichloroethylene (TCE) can lead to cellular toxicities. The type and severity of TCE transformation-dependent damage can have...
Resource Type:: Dissertation
Full Text:: : _______________________________________________ Daniel J. Arp Pseudomonas butanovora, Mycobacterium vaccae, and Nocardioides sp

Iron acquisition and its regulation in Nitosomonas europaea

Creator:: Vajrala, Neeraja
Abstract:: Iron is absolutely necessary for the maintenance, the defense, the differentiation and last, but by no means least, the growth and cellular division of almost all living organisms including Nitrosomonas europaea, an ammonia oxidizing bacterium. Given the necessity of iron, it is not surprising that N. europaea evolved several irondependent...
Resource Type:: Dissertation
Full Text:: europaea Abstract approved: __________________________________________________ Daniel J. Arp

Functional, structural and evolutionary analyses of the ferritin-like superfamily of proteins

Creator:: Cooley, Richard Bleier
Abstract:: The ferritin-like superfamily (FLSF) of proteins is composed of a wide variety of functionally diverse proteins involved in oxygen dependent metal-mediated electron transfer reactions. Their biological importance is exemplified by the fact FLSF proteins are found in almost every organism from all three domains of life. Their functions range from...
Resource Type:: Dissertation
Full Text:: : . Daniel J. Arp The ferritin-like superfamily (FLSF) of proteins is composed of a wide variety of

Mycobacterium tuberculosis Selective Adenosine Kinase Nucleoside Polymers for Inhalation Therapy

Creator:: Snow, Erika
Abstract:: Respiratory illnesses caused by both viral and bacterial infection are serious issues for global healthcare providers. With the emergence of new, drug-resistant forms of these diseases, innovative drugs and treatment therapies are needed. M tuberculosis is an infection that affects a large portion of the world’s population each year. Aerosol...
Resource Type:: Presentation and Undergraduate Thesis

Biochemical, molecular and physiological characterization of 1-butanol dehydrogenases of Pseudomonas butanovora in butane and 1-butanol metabolism

Creator:: Vangnai, Alisa S.
Abstract:: Butane-grown Pseudomonas butanovora oxidized butane by a soluble butane monooxygenase through the terminal pathway yielding 1 -butanol as the predominant product. Alcohol dehydrogenases (ADHs) involved in butane oxidation in P. butanovora were purified and characterized at the biochemical, genetic and physiological levels. Butane-grown P. butanovora expressed a type I soluble...
Resource Type:: Dissertation
Full Text:: Butane and 1 -Butanol Metabolism. Abstract approved: Daniel J.'Arp Butane-grown Pseudomonas

Physiological consequences of trichloroethylene degradation by the toluene-oxidizing bacterium Burkholderia cepacia G4

Creator:: Yeager, Chris M.
Abstract:: A number of bacterial species are capable of degrading the widespread environmental pollutant trichloroethylene (TCE) via aerobic cometabolism, but cytotoxic effects that can debilitate the microorganism often accompany this transformation. In this dissertation the effects of TCE degradation on the well-studied, toluene-oxidizing bacterium Burkholderia cepacia G4 were investigated at the...
Resource Type:: Dissertation
Full Text:: Abstract approved: Abstract approved: Daniel J. Arp Peter J. Bottomley A number of bacterial species

Diverse alkane monooxygenase systems in short-chain alkane-utilizing bacteria

Creator:: Hamamura, Natsuko
Resource Type:: Dissertation
Full Text:: Systems in Short-Chain Alkane-Utilizing Bacteria. Abstract approved: Daniel J. Arp Alkane

Cooxidation by three butane-grown bacteria and mechanism-based inactivation of butane monooxygenase

Creator:: Storfa, Ryan T.
Abstract:: Butane-grown cells of Pseudomonas butanovora, Nocardioides sp. CF8 and Mycobacterium vaccae JOB5 were tested for their ability to cooxidize methane, ammonia and ethylene. Less than 10 nmol of methane were degraded by each of the bacteria (0.17-0.35 mg protein) in 30 minutes. Hydroxylamine and nitrite accumulated when Nocardioides CF8 and...
Resource Type:: Masters Thesis
Full Text:: -----r;r------ Redacted for Privacy Daniel J. Arp Butane-grown cells of Pseudomonas butanovora

Hydrogenase in Azotobacter vinelandii : the role of the heme ligands in HoxZ

Creator:: Meek, Laura
Resource Type:: Dissertation
Full Text:: Role of the Heme Ligands in HoxZ c:r D~J. Arp ~ Hydrogenase catalyzes the reaction Hz ~ 2H+ + 2e

Properties of methyl bromide cooxidation by ammonia-oxidizing bacteria

Creator:: Duddleston, Khrystyne Noel
Resource Type:: Dissertation
Full Text:: AMMONIA-OXIDIZING BACTERIA. Abstract approved: Abstract approved: Peter J. Bottomley Daniel J. The

ScholarsArchive@OSU

Investigating the basis of substrate specificity in butane monooxygenase and chlorinated ethene toxicity in Pseudomonas butanovora

Iron acquisition and its regulation in Nitosomonas europaea

Functional, structural and evolutionary analyses of the ferritin-like superfamily of proteins

Mycobacterium tuberculosis Selective Adenosine Kinase Nucleoside Polymers for Inhalation Therapy

Biochemical, molecular and physiological characterization of 1-butanol dehydrogenases of Pseudomonas butanovora in butane and 1-butanol metabolism

Physiological consequences of trichloroethylene degradation by the toluene-oxidizing bacterium Burkholderia cepacia G4

Diverse alkane monooxygenase systems in short-chain alkane-utilizing bacteria

Cooxidation by three butane-grown bacteria and mechanism-based inactivation of butane monooxygenase

Hydrogenase in Azotobacter vinelandii : the role of the heme ligands in HoxZ

Properties of methyl bromide cooxidation by ammonia-oxidizing bacteria

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