Index Catalog // ScholarsArchive@OSU

Product formulations and in vitro-in vivo evaluation of 1) topical insect repellent formualtions against mosquitoes; 2) oral sustained release formulations of cefaclor and pentoxifylline in adults

Creator:: Chou, Joyce Tian-wei
Resource Type:: Dissertation
Full Text:: -toluamide (97% m-DEET) and Biphenyl (Sigma Chemical Co., St. Louis, MO), HPLC grade acetonitrile

Development and in vivo testing of novel hydrochlorothiazide gastric retention formulations in healthy volunteers and stage I hypertensive patients

Creator:: Farid, Samar Farghali
Abstract:: This thesis describes in vitro and in vivo evaluation of a gastric retention formulation (GRF) developed at Oregon State University. The formulation was prepared from xanthan gum and locust bean gum as gelling agents and other formulation ingredients were added, then it was originally vacuum oven dried. The effect of...
Resource Type:: Dissertation
Full Text:: Hypertensive Patients. Abstract Approved: James W This thesis describes in vitro and in vivo evaluation of a

Pharmacokinetic modeling and simulations of gastrointestinal transit effects on drug pharmacokinetics from enteric-coated pellet formulations and their applications

Creator:: Watanalumlerd, Prapoch
Abstract:: Effects of gastrointestinal transit on plasma concentrations of drugs from enteric-coated pellet formulations were demonstrated using pharmacokinetic models describing plasma concentrations of drugs from various enteric-coated pellet formulations. Gastric emptying time, lag time of emptying, and drug release rate from pellets in the small intestine, along with other pharmacokinetic parameters...
Resource Type:: Dissertation
Full Text:: Formulations 3) Development of Leaky Enteric-Coated Pellets Formulations Abstract James W. Effects of

Evaluation of gastrointestinal transit time and novel oral acetaminophen product formulation

Creator:: Hossain, Mohammad
Abstract:: Gastrointestinal (GI) transit data were collected using pigs as animal models. Density and size effects of non-disintegrating dosage forms on GI transit were investigated. Total GI transit times range from 2 to 33 days for 22 administrations of these nondisintegrating dosage forms. Pigs are found to not be an appropriate...
Resource Type:: Dissertation
Full Text:: Novel Oral Acetaminophen Product Formulation. Abstract approved: ,Redacted for Privacy James W. Ayres

Bioadhesive polymers in drug product formulations

Creator:: Tavipatana, Wattanaporn
Abstract:: Gastric retention time of single unit dosage forms in swine was found to be much longer than in humans. It was concluded that swine are not a good animal model to study GI transit time of nonerodable or slowly eroded dosage forms. Noneradable and slowly eroded dosage forms used to...
Resource Type:: Dissertation
Full Text:: approved: _Redacted for Privacy ((/ James W. Ayres, Ph /. / Gastric retention time of single unit dosage

Pharmacokinetics and pharmacodynamics of: 1) Oral sustained release acetaminophen suspension in children; 2) Potassium chloride in adults

Creator:: Kalns, John Eric
Resource Type:: Dissertation
Full Text:: ., St. Louis, MO.) dissolved in 700 ml 95% ethanol USP. Polyvinylpyrrolidinone (2% w/w), MW 40,000 and

In vitro and in vivo testing of a gastric retention device : development and evaluation of a new colonic delivery system

Creator:: Ahmed, Iman Saad
Abstract:: This thesis describes evaluation of a gastric retention device (GRD) developed at Oregon State University. The device was originally fabricated from Xanthan gum and Locust bean gum. A modified gastric retention device containing other additives was developed and investigated in this work. The modified device was evaluated in vitro for...
Resource Type:: Dissertation
Full Text:: W. Ayres 4 ABSTRACT A gastric retention device (GRD) fabricated from cross-linked carbohydrate

A novel self-sealing chewable sustained release tablet of acetaminophen ; Development and evaluation of novel itraconazole oral formulations ; A novel zero order release matrix tablet

Creator:: Rakkanka, Vipaporn
Abstract:: This thesis describes evaluation of a novel self-sealing chewable sustained release tablet that can maintain controlled release of drug regardless of compaction, crushing, or chewing. The new formulation contains polyethylene oxide which produces a sealant effect for cracks produced in the polymer coating during compaction. Dissolution studies were conducted and...
Resource Type:: Dissertation
Full Text:: Oral Formulations, (3) A Novel Zero Order Release Matrix Tablet. Abstract approved James W This

New product formulations, pharmacokinetics and bioavailability of dyphylline

Creator:: Chang, Shyi-Feu
Abstract:: Product formulation and in vitro dissolution characteristics of sustained-release chewable tablet dosage forms are presented in chapter one of this thesis. In vivo single dose and multiple dose studies of two sustained-release formulations as well as one conventional dyphylline formulation are described in chapter two. The pharmacokinetics of dyphylline following...
Resource Type:: Dissertation
Full Text:: Bioavailability of Dvohvlline Redacted for PrivacyAbstract approved: Product UJames w. Ayres formulation and

Prolonged duration of action of dyphylline through prodrugs

Creator:: Panomvana, Duangchit
Resource Type:: Dissertation
Full Text:: . Redacted for privacyAbstract approved: ?'Dr. James W. Ayres A series of four diesJrs and four monoesters

ScholarsArchive@OSU

Product formulations and in vitro-in vivo evaluation of 1) topical insect repellent formualtions against mosquitoes; 2) oral sustained release formulations of cefaclor and pentoxifylline in adults

Development and in vivo testing of novel hydrochlorothiazide gastric retention formulations in healthy volunteers and stage I hypertensive patients

Pharmacokinetic modeling and simulations of gastrointestinal transit effects on drug pharmacokinetics from enteric-coated pellet formulations and their applications

Evaluation of gastrointestinal transit time and novel oral acetaminophen product formulation

Bioadhesive polymers in drug product formulations

Pharmacokinetics and pharmacodynamics of: 1) Oral sustained release acetaminophen suspension in children; 2) Potassium chloride in adults

In vitro and in vivo testing of a gastric retention device : development and evaluation of a new colonic delivery system

A novel self-sealing chewable sustained release tablet of acetaminophen ; Development and evaluation of novel itraconazole oral formulations ; A novel zero order release matrix tablet

New product formulations, pharmacokinetics and bioavailability of dyphylline

Prolonged duration of action of dyphylline through prodrugs

Limit your search

Academic Affiliation

Advisor

Commencement Year

Committee Member

Creator

Date

Decade

Degree Field

Degree Level

Degree Name

File Format

Language

License

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search