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Filtering by: Creator Jenkins, Jack Advisor Ayres, James W.

In vitro and in vivo testing of a gastric retention device : development and evaluation of a new colonic delivery system

Creator:

Ahmed, Iman Saad

Abstract:

This thesis describes evaluation of a gastric retention device (GRD) developed at Oregon State University. The device was originally fabricated from Xanthan gum and Locust bean gum. A modified gastric retention device containing other additives was developed and investigated in this work. The modified device was evaluated in vitro for...

Resource Type:

Dissertation

Full Text:

................................................................................. 51 1.19 Radiograph showing the GRD in the stomach of Jack (A) ..................... 52 1.20 Lateral
New product formulations, pharmacokinetics and bioavailability of dyphylline

Creator:

Chang, Shyi-Feu

Abstract:

Product formulation and in vitro dissolution characteristics of sustained-release chewable tablet dosage forms are presented in chapter one of this thesis. In vivo single dose and multiple dose studies of two sustained-release formulations as well as one conventional dyphylline formulation are described in chapter two. The pharmacokinetics of dyphylline following...

Resource Type:

Dissertation
New product formulations and pharmacokinetics of acetaminophen

Creator:

Borin, Marie T.

Resource Type:

Dissertation