Index Catalog // ScholarsArchive@OSU

New product formulations, pharmacokinetics and bioavailability of dyphylline

Creator:: Chang, Shyi-Feu
Abstract:: Product formulation and in vitro dissolution characteristics of sustained-release chewable tablet dosage forms are presented in chapter one of this thesis. In vivo single dose and multiple dose studies of two sustained-release formulations as well as one conventional dyphylline formulation are described in chapter two. The pharmacokinetics of dyphylline following...
Resource Type:: Dissertation
Full Text:: /tablet)) in pigs 1, 2, and 3; data were derived by Wagner-Nelson method 11.6 Percent dyphylline

The absolute bioavailability of dyphylline tablets in human subjects

Creator:: Huston, Thomas K.
Abstract:: Dyphylline has been shown to be rapidly and completely absorbed from oral tablets in an absolute bioavailability study. In a pilot study two healthy male subjects received 1000 mg of dyphylline via intravenous infuson at a rate of 50 mg/min (1.0 ml/min) for 20 minutes. Plasma samples were collected for...
Resource Type:: Masters Thesis
Full Text:: . Comparisons were made between Ka obtained from one compartment and two compartment modeling (29), Wagner

Formulation and pharmacokinetics of melatonin

Creator:: Konsil, Julraht
Resource Type:: Dissertation

New product formulations and pharmacokinetics of acetaminophen

Creator:: Borin, Marie T.
Resource Type:: Dissertation
Full Text:: plasma concentrations of 10 to 20 pg/ml (Wagner, 1975) but is 15 to 21% bound at a plasma concentration

Assay and pharmacokinetics of dyphylline following oral administration in humans

Creator:: Gisclon, Lee Gehl
Abstract:: Improved assay methods for determination of dyphylline levels in plasma, saliva, and urine utilizing high pressure liquid chromatography have been developed. Detection of levels as low as 25 ng/ml from 0.5 ml plasma and 50 ng/ml from 0.5 ml saliva were possible. Both procedures utilized the same extraction process. A...
Resource Type:: Masters Thesis
Full Text:: ., and Wagner, J.G. (1977). High-pressure liquid chromatographic (HPLC) determination of tolmetin and its

Calcium alginate gels in oral dosage form design

Creator:: Lin, Shun Yih
Abstract:: In vivo research following ingesting of commercially available Lactobacillus tablets, which contain about 2X10⁶ cfu/tablet of Lactobacillus acidophilus and Lactobacillus bulgaricus cells in a dose of four tablets daily, showed serum lipoprotein concentrations did not change significantly. In order to increase the number of viable Lactobacillus bacteria after challenging in...
Resource Type:: Dissertation

Bioavailability and pharmacokinetics of dyphylline and theophylline in rabbits

Creator:: Mayo, Charles Edward
Abstract:: The bioavailability and pharmacokinetics of theophylline in rabbits were determined following both oral and intravenous administration of the drug. Serum theophylline concentrations were determined using high pressure liquid chromatography. Pharmacokinetic parameters were determined and verified by computer analysis. The overall mean Beta disposition constant was 0.089 hr⁻¹ which corresponds to...
Resource Type:: Masters Thesis
Full Text:: fluids were enzyme free. 30 RESULTS Ann DISCUSSION Dyphylline was administered as single dose

Pharmacokinetic/pharmacodynamic modeling/simulation and novel gastric retention formulation

Creator:: Kwon, Hyojong
Abstract:: This dissertation describes formulation of a gastric retention device (GRD) and sustained release (SR) hydrochlorothiazide beads at Oregon State University. Formulation condition and amounts of excipients had significant influence on characteristic of the GRD. The GRD containing SR hydrochlorothiazide beads was employed to assess bioavailability/bioequivalency study in healthy subjects. An...
Resource Type:: Dissertation

Prolonged duration of action of dyphylline through prodrugs

Creator:: Panomvana, Duangchit
Resource Type:: Dissertation

Pharmacokinetics of theophylline and it's N-7 derivatives in rabbits

Creator:: Tavipatana, Wattanaporn
Abstract:: Pharmacokinetics of theophylline and N-7 substituted theophylline in rabbits when administered alone and in various combinations were investigated. This thesis has four chapters dealing with etophylline and theophylline; proxyphylline and theophylline; dyphylline and theophylline; and etophylline, proxyphylline and dyphylline pharmacokinetics when administered concomitantly. All chapters are interrelated. Each chapter has...
Resource Type:: Masters Thesis

ScholarsArchive@OSU

New product formulations, pharmacokinetics and bioavailability of dyphylline

The absolute bioavailability of dyphylline tablets in human subjects

Formulation and pharmacokinetics of melatonin

New product formulations and pharmacokinetics of acetaminophen

Assay and pharmacokinetics of dyphylline following oral administration in humans

Calcium alginate gels in oral dosage form design

Bioavailability and pharmacokinetics of dyphylline and theophylline in rabbits

Pharmacokinetic/pharmacodynamic modeling/simulation and novel gastric retention formulation

Prolonged duration of action of dyphylline through prodrugs

Pharmacokinetics of theophylline and it's N-7 derivatives in rabbits

Limit your search

Academic Affiliation

Advisor

Commencement Year

Committee Member

Creator

Date

Decade

Degree Field

Degree Level

Degree Name

Language

License

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search