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Filtering by: Creator Wong, George Kaon Remove constraint Creator: Wong, George Kaon Advisor Bailey, George S. Remove constraint Advisor: Bailey, George S. Degree Field Biochemistry and Biophysics Remove constraint Degree Field: Biochemistry and Biophysics

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  • Analysis of ras gene mutations in rainbow trout tumors

    Creator:
    Chang, Yung-jin
    Abstract:
    For ras gene mutation analysis in the rainbow trout (Oncorhynchus mykiss) model system, a partial trout ras sequence was identified using the polymerase chain reaction (PCR). Two synthetic oligonucleotides based on rat K-ras gene sequence were used as primers for the PCR procedure. A 90 base pair (bp) sequence, referred...
    Resource Type:
    Dissertation
    Full Text:
    Tumors. Abstract approved : Redacted for Privacy George S. Bailey For ras gene mutation analysis in

  • Site-specific aflatoxin B₁ adduction of sequence-positioned nucleosome core particles

    Creator:
    Moyer, Richard A.
    Abstract:
    The question of how the presence of nucleosomal packing of DNA modifies carcinogen interaction at specific sites cannot be answered by studies on whole chromatin or bulk nucleosomes because of the heterogeneity of DNA sequences in the particles. This problem was circumvented by constructing nucleosomes that are homogenous in DNA-histone...
    Resource Type:
    Dissertation
    Full Text:
    privacy George T. Bailey The question of how the presence of nucleosomal packing of DNA modifies