Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Creator Sun, Mindy Advisor Baird, William M. License All rights reserved

DNA binding and beyond : an investigation of proteins involved in PAH-induced carcinogesesis

Creator:

Hooven, Louisa Ada

Abstract:

Exposure to polycyclic aromatic hydrocarbons such as benzo[a]pyrene (B[a]P) has been determined to be a risk factor for various forms of human cancer. PAH DNA adducts have been shown to cause mutations, but carcinogenesis is also accompanied by alterations in gene expression. Inhibiting individual cytochrome P450s could clarify the interaction...

Resource Type:

Dissertation