Index Catalog // ScholarsArchive@OSU

Creator:: Jie, Jing
Abstract:: Intrinsically disordered proteins (IDP) are a class of proteins that lack a three-dimensional structure and their prevalence and diverse functions in the cell have only been discovered relatively recently. The intermediate chain (IC) subunit of the microtubule motor protein complex dynein contains an N-terminal disordered region, N-IC, which is central...
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE DISSERTATION OF Jing Jie for the

Creator:: Jara, Kayla A.
Abstract:: Intrinsically disordered proteins (IDPs), protein regions (IDRs), and protein complexes continue to emerge at the forefront of protein science. Proteins and protein regions lacking specific structure are found in all organisms, and often have vital roles in numerous biological processes. Breaking the well-known structure-function paradigm, the understanding of disorder-based functionality...
Resource Type:: Dissertation

Creator:: Clark, Sarah A.
Abstract:: Hub proteins bind a large number of partners to facilitate structural changes and downstream protein interactions. LC8, a highly conserved protein homodimer, is a unique hub that regulates the activity of proteins in a wide range of cellular processes by binding to intrinsically disordered regions. With many of these systems,...
Resource Type:: Dissertation
Full Text:: and Dr. Jing Jie, for their infinite patience, amazing organizational skills, and willingness to

Creator:: Morgan, Jessica L.
Abstract:: Cells represent microcosms of spatial and temporal structural organization, with the achievement of internal spatial organization relying upon a collection of macromolecular motor complexes to transport and localize components throughout the cell. Cytoplasmic dynein is one such motor complex, and is the principal ATP-dependent motor for retrograde transport along microtubules...
Resource Type:: Dissertation
Full Text:: labmates, Yujuan Song and Jing Jie. I thank Yujuan for being both a friend and a mentor to me in the lab

ScholarsArchive@OSU