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Filtering by: Creator Rubin, Meyer Advisor Barofsky, Douglas F. Degree Name Doctor of Philosophy (Ph.D.)

Chlordecone pretreatment promoted subcellular distribution of scavenger receptor class B type II to murine hepatic microsomes ; mass spectrometry detected hepatic soluble cholesterol binding proteins and comparison of protein iTRAQ ratios using ESI QTOF and MALDI TOF/TOF

Creator:

Scheri, Richard C.

Abstract:

Chlordecone belongs to the class of persistent organochlorine pesticides that are remarkably resistant to environmental degradation. Even though their use was banned in the United States in 1978, these compounds can still be detected in both humans and wildlife throughout the world. Previous work has shown that the pretreatment of...

Resource Type:

Dissertation
Characterization of photochemically cross-linked protein-nucleic acid complexes by mass spectrometry

Creator:

Jensen, Ole Norregaard

Abstract:

A novel protocol for the study of protein-nucleic acid interactions is presented and demonstrated to be feasible. The protocol combines photochemical crosslinking techniques and mass spectrometric methods into a new strategy for identifying protein domains or amino acid residues that are in close contact with nucleic acid in protein-nucleic acid...

Resource Type:

Dissertation