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Filtering by: Advisor Bermudez, Luiz E. Date 2006 Rights Statement Copyright Not Evaluated

Macrophage infection with wild-type Mycobacterium avium or isogenic attenuated PPE mutant revealed differences in gene expression and mycobacterial vacuole proteins

Creator:

Jha, Samradhni

Abstract:

Mycobacterium avium is a ubiquitous environmental organism found in water and soil. It can cause disease in patients with pre-existing pulmonary conditions, immunocompromised patients with the most prevalent being AIDS patients, as well as apparently healthy people. Studies have indicated that, upon macrophage uptake, Al. avium prevents phagosome-lysosome fusion, thus...

Resource Type:

Masters Thesis