Index Catalog // ScholarsArchive@OSU

Characterization of Mycobacterium avium subsp. hominissuis Interactions with Host Macrophages and Multinucleated Giant Cells

Creator:: Joseph, Jayanthi J.
Abstract:: To examine the macrophage response to M. avium, I compared inflammasome and cytosolic sensor expression and activation. My result demonstrated that virulent strains of M. avium (A5 and 104) suppress IL-1β production and induce IFN-β production in macrophages. M. avium mutants deficient at DNA export in the biofilm exhibited reduced...
Resource Type:: Dissertation
Full Text:: inflammasome leads to cell death by pyroptosis or necroptosis (Swanson et al., 2019, p. 3; Wong & Jacobs Jr

Characterization of microaggregate formation by Mycobacterium avium subspecies hominissuis

Creator:: Babrak, Lmar
Abstract:: Mycobacterium avium subsp hominissuis (MAH) is an opportunistic environmental pathogen that causes respiratory and gastrointestinal illness in immunocompromised persons such as those with chronic respiratory diseases or AIDs, respectively. In recent years, there has been a significant increase in the incidence of nontuberculous mycobacterial (NTM) lung infections, including in cystic...
Resource Type:: Dissertation
Full Text:: ........................ 162 Appendix 1.2 Bannatine JP, Everman JL, Rose SJ, Babrak L Katani R, Barletta RG, Talaat AM

Characterization of Membrane Vesicles Released by the Opportunistic Human Pathogen Mycobacterium avium subsp. hominissuis (MAH) in Response to an in vitro System Mimicking the Phagosomal Environment

Creator:: Chiplunkar, Sanket S.
Abstract:: Mycobacterium avium subsp. hominissuis (MAH) belongs to the most-clinically significant non-tuberculous mycobacterial (NTM) pathogens with constant increase in disease prevalence, mainly in several industrialized western countries where tuberculosis is less prevalent. Upon entry into the alveolar space, MAH is engulfed by resident-macrophages, where the pathogen adapts to the hostile phagosomal...
Resource Type:: Masters Thesis

Disease models and infectious phenotypes of Mycobacterium avium subspecies paratuberculosis

Creator:: Everman, Jamie L.
Abstract:: Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne's disease, a chronic inflammatory bowel disease that affects ruminant populations worldwide. The characteristic stages of the disease make diagnosis difficult, resulting in silent transmission among animals in a herd for years before proper detection of the infection. The extensive...
Resource Type:: Dissertation
Full Text:: , Rose SJ, Babrak L, Katani R, Barletta RG, Talaat AM, Gröhn YT, Chang Y-F, Kapur V and Bermudez LE

Mycobacterium avium genes upregulated upon infection of Acanthamoeba castellanii demonstrate a common response to the intracellular environment

Creator:: Tennant, Rachel C.
Abstract:: Mycobacterium avium is a ubiquitous environmental organism found in both water and soil. It can cause disease in patients with previous pulmonary conditions, as well as immunosupressed patients, with the most prevalent being AIDS patients. Studies have indicated that passage through amoeba, a common environmental protozoa, increases virulence of M....
Resource Type:: Masters Thesis
Full Text:: of Rachel C. Tennant presented on March 4, 2005. r tsyjtjj Major Profesor, represnting Microbiology

Macrophage infection with wild-type Mycobacterium avium or isogenic attenuated PPE mutant revealed differences in gene expression and mycobacterial vacuole proteins

Creator:: Jha, Samradhni
Abstract:: Mycobacterium avium is a ubiquitous environmental organism found in water and soil. It can cause disease in patients with pre-existing pulmonary conditions, immunocompromised patients with the most prevalent being AIDS patients, as well as apparently healthy people. Studies have indicated that, upon macrophage uptake, Al. avium prevents phagosome-lysosome fusion, thus...
Resource Type:: Masters Thesis

Establishment of an in vitro System for Studying Mycobacterium avium Protein Secretion

Creator:: Chinison, Jessica J.
Abstract:: Cases of pulmonary diseases caused by Mycobacterium avium complex (MAC) have increased over the years and have become a major health concern in Europe, Asia, and the United States. MAC, comprised of M. avium species and M. intracellulare, are found everywhere in the environment: in water sources and the soil....
Resource Type:: Masters Thesis
Full Text:: .” Mol Biol 83(6): 1195-1209. Braunstein, M., A. M. Brown, S. Kurtz, W. R. Jr. Jacobs (2001). “Two

Molecular and cellular characterization of the intracellular phenotype of Mycobacterium avium

Creator:: Early, Julie V.
Abstract:: Mycobacterium avium cause disseminated disease in immunocompromised people such as AIDS patients. Subsequent to crossing the intestinal epithelium, M. avium thrive within vacuoles in macrophages. The bacteria exhibit a different, more invasive, phenotype after being in macrophages compared to M. avium from laboratory conditions. We hypothesized that this intracellular phenotype...
Resource Type:: Dissertation
Full Text:: , Bildfell R, Arbogast B, Bermudez LE. Identification of Mycobacterium avium pathogenicity island important

Surface-exposed proteins in the pathogenesis of Mycobacterium avium subsp. hominissuis

Creator:: McNamara, Michael J.
Abstract:: Mycobacterium avium subsp. hominissuis (MAH) is a pervasive environmental bacterium that can cause opportunistic infections in humans. Among the most robust and hardy members of the Mycobacterium genus, M. avium can persist and thrive in a range of challenging environments, including many which place it in direct contact with humans....
Resource Type:: Dissertation
Full Text:: range of un- folded precursor proteins that contain a conserved N-terminal signal sequence (S/T- R-R-X

ScholarsArchive@OSU

Characterization of Mycobacterium avium subsp. hominissuis Interactions with Host Macrophages and Multinucleated Giant Cells

Characterization of microaggregate formation by Mycobacterium avium subspecies hominissuis

Characterization of Membrane Vesicles Released by the Opportunistic Human Pathogen Mycobacterium avium subsp. hominissuis (MAH) in Response to an in vitro System Mimicking the Phagosomal Environment

Disease models and infectious phenotypes of Mycobacterium avium subspecies paratuberculosis

Mycobacterium avium genes upregulated upon infection of Acanthamoeba castellanii demonstrate a common response to the intracellular environment

Macrophage infection with wild-type Mycobacterium avium or isogenic attenuated PPE mutant revealed differences in gene expression and mycobacterial vacuole proteins

Establishment of an in vitro System for Studying Mycobacterium avium Protein Secretion

Molecular and cellular characterization of the intracellular phenotype of Mycobacterium avium

Surface-exposed proteins in the pathogenesis of Mycobacterium avium subsp. hominissuis

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