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Filtering by: Committee Member Greenwood, Jeffery A Advisor Blakemore, Paul R.

Investigation of Chain Extension Approaches for the Stereoselective Reagent-Controlled Synthesis of alpha-Heteroatom Substituted Alkyl Boronic Esters

Creator:

Barsamian, Adam L.

Abstract:

Two distinct strategies were explored for the enantioselective synthesis of α-heteroatom substituted alkyl boronic esters by stereoselective reagent-controlled homologation using transient chiral carbenoid reagents CHYMX (Y = heteroatom, X = nucleofuge, M = electrofuge). In the first case, a stereospecific reagent-controlled homologation (sStReCH) approach to α-alkoxyalkylboronates using α-metalated S,O- and...

Resource Type:

Dissertation

Full Text:

case, a stereospecific reagent-controlled homologation (sStReCH) approach to α-alkoxyalkylboronates