Search Constraints

Start Over
Filtering by: Creator Olden, Julian D. Remove constraint Creator: Olden, Julian D. Advisor Bovbjerg, Viktor E. Remove constraint Advisor: Bovbjerg, Viktor E. Contributor Tyner, Jeffrey Remove constraint Contributor: Tyner, Jeffrey Degree Level Bachelor's Remove constraint Degree Level: Bachelor's

Search Results

  • Role of MEK Mutations in Trametinib Resistant Acute Myeloid Leukemia Cells

    Creator:
    Beer, Sofia R.
    Abstract:
    Acute myeloid leukemia (AML) is a blood malignancy characterized by a differentiation and proliferation defect of myeloid progenitors leading to accumulation of myeloid blasts. It is one of the most common leukemias in adults. Trametinib (Mekinist) is a small molecule inhibitor that targets MEK1 (MAP2K1) and MEK2 (MAPK2K2). It has...
    Resource Type:
    Honors College Thesis
    Full Text:
    /cationic-lipid-mediated- delivery.html 4. Dohner, G., Weisdorf, D., & Bloomfield, C. D. (2015). “Acute