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Filtering by: Alternative title ssim EC 1196 Advisor Buhler, Donald R.

Comparative metabolism of the pyrrolizidine alkaloid senecionine in rat and guinea pig

Creator:

Chung, Woon-Gye

Resource Type:

Dissertation
Toxicity and in vitro metabolism of Senecio jacobaea pyrrolizidine alkaloids in the rat and mouse

Creator:

Ramsdell, Howard Scott

Abstract:

Senecio jacobaea (tansy ragwort) is a common weed in the Pacific Northwest that contains toxic pyrrolizidine alkaloids (PAs). Jacobine, the major PA in Senecio jacobaea, was incubated with rat liver microsomes and metabolites were isolated by high performance liquid chromatography (HPLC) and identified by mass spectrometric analysis. Metabolites included a...

Resource Type:

Dissertation