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Filtering by: Creator Ryu, Jeong-Gon Advisor Burrows, Sean M. Degree Field Chemistry

Displacement-based fluorescent microRNA biosensors : design principles and analytical metrics

Creator:

Larkey, Nicholas E.

Abstract:

One post-transcriptional mechanism that regulates the progression of cancer and other diseases involves small 22-23 nucleotide sequences called microRNA (miR). Early detection of small changes in concentration of these biomarkers holds potential to diagnose diseases at their earliest stages. Use of current nucleic-acid based biosensors, like molecular beacons, for in...

Resource Type:

Dissertation