Search Constraints

Start Over
Filtering by: Committee Member Thompson, M. Paul Remove constraint Committee Member: Thompson, M. Paul Advisor Carter, Rich G. Remove constraint Advisor: Carter, Rich G.

Search Results

  • A unified approach for the total synthesis of C₁₀-functionalyzed Lycopodium alkaloids

    Creator:
    Saha, Mrinmoy
    Abstract:
    Lycopodium alkaloids have shown widespread and noteworthy biological activity, consisting of over 250 known natural products. Moreover, their structural complexity and diversity have attracted considerable attention from numerous laboratories including our own. Recently, we have developed a unified approach that would provides access to numerous, previously unprepared C₁₀-functionalized lycopodium alkaloids....
    Resource Type:
    Dissertation
    Full Text:
    ) Nikonorow, M. Acta Polon. Pharm. 1939, 3, 23-56. (d) Ortega, M. G.; Agnese, A. M.; Cabrera, J. L

  • Enantioselective Total Syntheses of Quinolizidine Lycopodium Alkaloid Cermizine D and Cytotoxic Marine Macrolide Mandelalide A

    Creator:
    Veerasamy, Nagarathanam
    Abstract:
    The enantioselective total synthesis of quinolizidine-containing natural product cermizine D and formal syntheses of senepodine G and cermizine C has been achieved. These natural products are members of the lycopodium alkaloids, which have attracted significant attention due to their exciting biological activities and the diverse structural scaffolds. Key steps in...
    Resource Type:
    Dissertation
    Full Text:
    .) THF, 60 °C; 3 M HCl in MeOH 98% N H Cl NaBH4, MeOH 99% N H (-)-Cermizine C (1.9) 1.1.1 1.1.3

  • Synthetic studies toward the total synthesis of azaspiracid-1

    Creator:
    Su, Dong
    Abstract:
    Azaspiracid-1, a novel marine toxin that contains 9 rings and 20 stereogenic centers, has drawn considerable attention from synthetic groups worldwide due to its structural complexity, which includes a unique trioxabisspiroketal fused to a tetrahydrofuran ring (ABCD rings), a piperidine-tetrahydrofuran spiroaminal system fused to a 2,9-dioxabicyclo[3.3.1]nonane system (FGHI rings), a...
    Resource Type:
    Masters Thesis