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Filtering by: Advisor Crannell, Wanda Creator Brodeur, Timothy J. Degree Level Bachelor's Resource Type Undergraduate Thesis

DNA mismatch repair and 0[superscript 6]-methylguanine toxicity : Testing the futile repair cycle hypothesis

Creator:

Brodeur, Timothy J.

Abstract:

Cell lines deficient in certain genes of the DNA mismatch repair (MMR) system show a marked resistance to the cell killing or apoptotic effects of DNA alkylating agents. The molecular mechanism for this resistance is not yet understood, but is currently of great interest because of the recent use of...

Resource Type:

Undergraduate Thesis