Index Catalog // ScholarsArchive@OSU

Chlordecone impaired biliary excretion : in vivo and in vitro correlates

Creator:: Rochelle, Lori G.
Resource Type:: Dissertation
Full Text:: Corvallis, Oregon 97331-3803 12 Abstract The effect of in vitro chlordecone (CD) treatment on hepatic

Developmental axial skeletal deformities : baseline study with a zebrafish model

Creator:: Harden, Jon M.
Abstract:: The aim of this study was to assess sensitivity of early life stage zebrafish to cadmium (Cd). Embryos and larva were exposed to Cd before the formation of skeletal elements. Exposure times were selected to determine whether Cd perturbed developmental processes that lead to skeletal deformities, and to characterize the...
Resource Type:: Masters Thesis
Full Text:: . There was no effect of Cd on incidence of any type of skeletal deformity at 4Odpf(P>O.05 and p>O.O5

Vitellogenesis : a biomarker for estrogenic and antiestrogenic effects of organochlorines in rainbow trout

Creator:: Donohoe, Regina M.
Abstract:: Persistent organochlorines (OCs) bioaccumulate in aquatic biota and potentially impair reproduction via endocrine disruption. The present research evaluated estrogenic effects of the OCs, chlordecone (CD) and o,p'-DDT/DDE, and the antiestrogenicity of 3,4,5,3',4',5'-hexachlorobiphenyl (345-HCB) in juvenile rainbow trout, utilizing vitellogenesis as a biomarker. Vitellogenesis, estrogen regulated hepatic production of the yolk...
Resource Type:: Dissertation
Full Text:: synthesis and lipid metabolism (Cyr et al., 1988) but no evidence of a direct effect on Vg synthesis is

Congener-specific disposition of polychlorinated biphenyls in rainbow trout

Creator:: Foster, Eugene P.
Resource Type:: Dissertation
Full Text:: fish (Zabel et al., 1995). Interactions of compounds with minimal effect on metabolizing enzyme

Alteration of cholesterol disposition by chlordecone is not explained by induction of cyp7a or cyp4a1

Creator:: Lee, JungA
Abstract:: Liver X receptor (LXR), farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor (PPAR) are adopted orphan nuclear receptors that function as lipid sensors. These receptors respond to cellular lipid levels and regulate the expression of target gene. Previously, it was demonstrated that low doses of chlordecone (CD) pretreatment disturbed exogenous...
Resource Type:: Masters Thesis
Full Text:: ). There was no significant effect of CD treatment on liver-to-body weight ratio calculated as liver

Alterations in mink reproductive physiology following exposure to coplanar and noncoplanar polychlorinated biphenyls (PCBs)

Creator:: Patnode, Kathleen A., 1959-
Abstract:: Female mink (Mustela vison) are highly sensitive to polychlorinated biphenyl (PCB)-induced reproductive impairment. The goal of this research was to develop a better understanding of the mechanism of PCB-induced effects on female mink, mink embryos, and surviving mink kits. Anestrous, juvenile female mink and pregnant, adult mink were exposed to...
Resource Type:: Dissertation
Full Text:: Kathleen A. Patnode for the degree of Doctor of Philosophy in Toxicology presented on May 4, 1995. Title

Bioaccumulation of dietary 2,2',4,4',5,5'-hexachlorobiphenyl and induction of hepatic aryl hydrocarbon hydroxylase in rainbow trout (oncorhynchus mykiss)

Creator:: da Costa, Emmanuel G.
Resource Type:: Masters Thesis
Full Text:: presented on July 20, 1994 Title: Bioaccumulation of Dietary 2,2',4,4',5,5'-Hexachlorobiphenyl and

Assessing mechanisms of immunotoxicity for polycyclic aromatic hydrocarbons in rainbow trout (Oncorhynchus mykiss)

Creator:: Bravo, Claudia F.
Abstract:: During the past 30 years, numerous studies have focused on the toxicities of polycyclic aromatic hydrocarbons (PAH). Laboratory and field studies have helped elucidate the detrimental effects of these chemicals on growth, reproduction and immune response. Polycyclic aromatic hydrocarbons are in the priority list of chemicals to be studied by...
Resource Type:: Dissertation
Full Text:: degree of Doctor of Philosophy in Toxicology presented on December 9. 2005. Title: Assessing Mechanisms

Semi-volatile organic compounds and developing organisms : accumulation in California mountain tadpoles in the field and fish embryo exposures in the laboratory

Creator:: Stanley, Kerri A.
Abstract:: The atmospheric transport and deposition of semi-volatile organic compounds (SOCs), including current and historic use pesticides, polychlorinated biphenyls (PCBs) and polycyclic aromatic hydrocarbons (PAHs), to mountain ecosystems may result in the exposure of tadpoles to these SOCs. This exposure has been implicated in amphibian population declines in California. Tadpoles encounter...
Resource Type:: Dissertation
Full Text:: responsible for most of the sediment sample preparation for chemical analysis for Chapter 3. Dr. Robert

Antioxidant enzyme response in rainbow trout (Oncorhynchus mykiss) after subchronic exposure to an environmentally-relevant polycyclic aromatic hydrocarbon mixture

Creator:: Norby, Tyler S.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are significant pollutants in aquatic environments. Many are carcinogenic and lead to DNA fragmentation and adduct formation in marine and freshwater organisms. Previous research demonstrates that rainbow trout (Oncorhynchus mykiss) compensate to long-term PAH dietary exposures and reduce the DNA damage. The aim of this study...
Resource Type:: Masters Thesis
Full Text:: previous research, there was no significant (P > 0.05) effect on body weight of the fish in any of the

ScholarsArchive@OSU

Chlordecone impaired biliary excretion : in vivo and in vitro correlates

Developmental axial skeletal deformities : baseline study with a zebrafish model

Vitellogenesis : a biomarker for estrogenic and antiestrogenic effects of organochlorines in rainbow trout

Congener-specific disposition of polychlorinated biphenyls in rainbow trout

Alteration of cholesterol disposition by chlordecone is not explained by induction of cyp7a or cyp4a1

Alterations in mink reproductive physiology following exposure to coplanar and noncoplanar polychlorinated biphenyls (PCBs)

Bioaccumulation of dietary 2,2',4,4',5,5'-hexachlorobiphenyl and induction of hepatic aryl hydrocarbon hydroxylase in rainbow trout (oncorhynchus mykiss)

Assessing mechanisms of immunotoxicity for polycyclic aromatic hydrocarbons in rainbow trout (Oncorhynchus mykiss)

Semi-volatile organic compounds and developing organisms : accumulation in California mountain tadpoles in the field and fish embryo exposures in the laboratory

Antioxidant enzyme response in rainbow trout (Oncorhynchus mykiss) after subchronic exposure to an environmentally-relevant polycyclic aromatic hydrocarbon mixture

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