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  • Crystallin proteolysis in lens during aging and cataract formation

    Creator:
    Ueda, Yoji
    Abstract:
    The major purpose of this research was to characterize partially degraded proteins appearing in the ocular lens during aging and cataract, and to identify the responsible proteolytic activities. This research is significant, because increased protein degradation is associated with lens opacification and cataract. Determining the sites where lens proteins become...
    Resource Type:
    Dissertation
    Full Text:
    field of proteomics. I would also like to thank Dr. Neil E. Forsberg, Dr. Philip D. Whanger, Dr