Search Constraints

Start Over
Filtering by: Advisor Dolan, Brian Remove constraint Advisor: Dolan, Brian Advisor Dolan, Brian P. Remove constraint Advisor: Dolan, Brian P.

Search Results

  • Crossing Boundaries during Stress Responses: Antigen Presentation by Adaptive and Innate MHC Class I Molecules

    Creator:
    Nagamine, Brandy S.
    Abstract:
    The immune system is a complex network of cellular processes working in harmony to guard us against pathogenic attack. Of utmost importance is the ability of the immune system to discriminate between “self” and “non-self” and diseased versus healthy. Recognition of antigens complexed to major histocompatibility complex (MHC) molecules is...
    Resource Type:
    Dissertation
    Full Text:
    : _____________________________________________________ Brian P. Dolan The immune system is a complex network of cellular processes working

  • Non-Canonical Nedd8 Conjugation Mediated Targeted Protein Degradation and Direct Antigen Presentation

    Creator:
    Vijayasimha, Kartikeya
    Abstract:
    While the role of ubiquitin in protein degradation is well established, the role of other ubiquitin-like proteins (UBLs) in protein degradation is less clear. Neural precursor cell expressed developmentally down-regulated protein 8 (NEDD8) is the UBL with the highest level of amino acid identity when compared to ubiquitin. Here we...
    Resource Type:
    Dissertation
    Full Text:
    Presentation. Abstract approved: ______________________________________________________ Brian P. Dolan

  • Investigating variation in immunity and infection risk in wild ungulates

    Creator:
    Dugovich, Brian S.
    Abstract:
    In the midst of the sixth mass extinction, understanding wildlife disease spillover is critical to maintaining protected wildlife areas. Studying ecoimmunology and wildlife disease ecology helps to understand immune and disease traits in an ecological context, which is invaluable in preventing pathogen spillover between livestock and wildlife. To investigate this...
    Resource Type:
    Dissertation
    Full Text:
    : ______________________________________________________ Anna E. Jolles Brian P. Dolan In the midst of the sixth mass extinction