Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Creator Hahn, Linda Advisor Dreher, Theo W. Committee Member Braunworth, Bill

Translation of dengue virus RNA : influence of the untranslated regions on 5´-cap dependent translation and ribosome scanning

Creator:

Chiu, Wei-Wei

Abstract:

In this thesis, I studied the translation of dengue virus RNA using a luciferase reporter gene system in Vero cells. The dengue reporter mRNA construct, which harbors 5´-terminal viral nts and 3´-terminal nts, could be translated efficiently compared to an alpha globin reporter construct. The 5´-cap structure and 3´-untranslated region...

Resource Type:

Dissertation

Full Text:

program. I am very grateful to Dr. Mary Burke and Dr. Linda Bruslind for helping me with the teaching