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Filtering by: Creator Shock, C. Remove constraint Creator: Shock, C. Advisor Estevez, Alvaro G. Remove constraint Advisor: Estevez, Alvaro G. License Attribution-NonCommercial-NoDerivatives 4.0 (CC BY-NC-ND 4.0) Remove constraint License: Attribution-NonCommercial-NoDerivatives 4.0 (CC BY-NC-ND 4.0)

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  • Addressing ALS: Corroborating the Methodology of Studying the P2X7R Complex

    Creator:
    Veytsman, Edward Y.
    Abstract:
    Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of motor neurons in the motor cortex and spinal cord. Recent evidence suggests that the purine receptor P2X7 (P2X7R) plays a central role in the pathology of ALS. Previous research indicates that P2X7R activation by oxidatively modified heat shock protein 90...
    Resource Type:
    Honors College Thesis
    Full Text:
    by oxidatively modified heat shock protein 90 (Hsp90) or Hsp90 inhibition stimulates motor neuron