Index Catalog // ScholarsArchive@OSU

Creator:: Peters, Alec
Abstract:: DNA segments in the fungus Fusarium graminearum were identified as possible genes encoding for chromodomain proteins (CDPs), and targeted for genetic manipulation. Targeted single-gene deletion strains, as wells as GFP-S tag fusion strains, were generated from wildtype F. graminearum protoplasts, and verified strains were screened for phenotypic differences, such as...
Resource Type:: Honors College Thesis
Full Text:: , Y., Selleck, W., Lane, W. S., Tan, S., Côté, J. (2004). Structural and Functional Conservation of

Creator:: Geisler, Mark S.
Abstract:: Histones, as part of nucleosomes, are responsible for DNA packaging in chromosomes. They also affect DNA expression by a multitude of post-translational modifications, especially prevalent on the amino terminus of histones. Co-activator protein complexes “write”, “read”, or “erase” histone modifications, and in balance determine which sections of DNA are free...
Resource Type:: Honors College Thesis
Full Text:: ). In S. pombe, Swi6 (HP1) is required for recruitment of the cohesion complex for segregation in

Creator:: Esposito, Madison L.
Abstract:: Modifications of histone tail amino acid residues are necessary for many reactions involving chromatin. These processes can produce transcriptionally active, euchromatic, or inactive, heterochromatic, segments of DNA. The formation and maintenance of facultative heterochromatin is critical for the proper growth and development of many eukaryotes. Euchromatin can be changed into...
Resource Type:: Undergraduate Thesis and Presentation
Full Text:: 36 P H R Y K P G T V A L R E I R R Y Q K S T E L L I R K L P F Q R L V R E I A Q D F K S

Creator:: Jackson, Kendra K.
Abstract:: PRC2 (Polycomb Repressive Complex 2) mediated gene silencing plays an important role in cell differentiation, stem cell plasticity, and tumor suppression. In fungi, it is also involved in pathogenicity. The catalytic subunit, KMT6, trimethylates lysine 27 on histone h3 (H3K27me3) at loci targeted for silencing. In animals, PRC1 and PRC2...
Resource Type:: Honors College Thesis
Full Text:: overnight expression at 18◦C after induction with 0.1mM IPTG. Fractions “S” and “P” refer to supernatant

ScholarsArchive@OSU