Index Catalog // ScholarsArchive@OSU

Creator:: Peters, Alec
Abstract:: DNA segments in the fungus Fusarium graminearum were identified as possible genes encoding for chromodomain proteins (CDPs), and targeted for genetic manipulation. Targeted single-gene deletion strains, as wells as GFP-S tag fusion strains, were generated from wildtype F. graminearum protoplasts, and verified strains were screened for phenotypic differences, such as...
Resource Type:: Honors College Thesis
Full Text:: fusion strains, were generated from wildtype F. graminearum protoplasts, and verified strains were

Creator:: Pomraning, Kyle R.
Abstract:: Mutation of repetitive DNA by repeat-induced point mutation (RIP) is a process that occurs in many filamentous fungi of the Ascomycota during the sexual cycle. Concurrently, direct DNA repeats are often deleted by homologous recombination at high frequency during the sexual cycle. Thus, the processes of RIP and deletion compete...
Resource Type:: Dissertation
Full Text:: strain of F. graminearum (00-676-2) and identified 62,310 single nucleotide polymorphisms (SNPs

Creator:: Esposito, Madison L.
Abstract:: Modifications of histone tail amino acid residues are necessary for many reactions involving chromatin. These processes can produce transcriptionally active, euchromatic, or inactive, heterochromatic, segments of DNA. The formation and maintenance of facultative heterochromatin is critical for the proper growth and development of many eukaryotes. Euchromatin can be changed into...
Resource Type:: Undergraduate Thesis and Presentation
Full Text:: K56Q K56R K56M K56L K64L Q68A Q68S K79Q K79R K79M K79L K122LE133A R134A F. graminearum will be used

Creator:: Geisler, Mark S.
Abstract:: Histones, as part of nucleosomes, are responsible for DNA packaging in chromosomes. They also affect DNA expression by a multitude of post-translational modifications, especially prevalent on the amino terminus of histones. Co-activator protein complexes “write”, “read”, or “erase” histone modifications, and in balance determine which sections of DNA are free...
Resource Type:: Honors College Thesis
Full Text:: (Lachner et al., 2001; Tamaru and Selker, 2001) (Lewis et al., 2009; Smith et al., 2011; Zhang et al

Creator:: Josephson, Brian
Abstract:: Polycomb Repressive Complex 2 (PRC2) is a histone methyltransferase that initiates facultative heterochromatin formation by trimethylating histone H3 on lysine 27 (H3K27me3). Mutations within its three primary subunits, KMT6, EED, and SUZ12, result in inherited diseases and sporadic cancers. In the fungus Fusarium graminearum, deletion of the gene encoding the...
Resource Type:: Honors College Thesis
Full Text:: haematococca; Fo5176Set7, Fusarium oxysporum [b and c are pseudogenes]; FvSet7, F. verticillioides

Creator:: Phatale, Pallavi A.
Abstract:: In eukaryotes, the defined loci on each chromosome, the centromeres, accomplish the critical task of correct cell division. In some organisms, centromeres are composed of a euchromatic central core region embedded in a stretch of heterochromatin and the inheritance and maintenance of centromeres are controlled by dynamic epigenetic phenomena. Although...
Resource Type:: Dissertation
Full Text:: on F and ParA on R1, to aid in DNA segregation by assembling a specific partitioning complex that

Creator:: Friedman, Steven
Abstract:: DNA is often described as the “blueprint for life”. In eukaryotes this information is contained within linear chromosomes of varying size and number. During cell division, the chromosomes must be faithfully segregated into each daughter cell to avoid disease and sustain life. This process is carried out by the kinetochore...
Resource Type:: Dissertation
Full Text:: ..................................................................... 93 Figure 4.2 Progress of mutant generation in N. crassa and F. graminearum ................... 94

Creator:: Bredeweg, Erin L.
Abstract:: Fungi are capable of growth on a wide variety of carbon sources, both living and dead. They can produce an arsenal of enzymes and transporters for harvesting sugars, polysaccharides, amino acids, lipids and micronutrients from their environments [1]. Within the nucleus of a cell, transcription factors (TF) control whether genes...
Resource Type:: Dissertation

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