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Filtering by: Creator Berman, T. Advisor Gerwick, William H. Creator Ramaswamy, Aishwarya V.

Cloning and biochemical characterization of the hectochlorin biosynthetic gene cluster from the marine cyanobacterium Lyngbya majuscula

Creator:

Ramaswamy, Aishwarya V.

Abstract:

Cyanobacteria are rich in biologically active secondary metabolites, many of which have potential application as anticancer or antimicrobial drugs or as useful probes in cell biology studies. A Jamaican isolate of the marine cyanobacterium, Lyngbya majuscula was the source of a novel antifungal and cytotoxic secondary metabolite, hectochlorin. The structure...

Resource Type:

Dissertation

Full Text:

) Bryostatin 1 (5) H2N NNH O0NH HN 0 O2NH 0 H / HN 'H 0 0 Y H 0 HO NH \ / O T N T ( T y Kahalalide F (7)0