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Filtering by: Alternative title ssim EC 1141 Remove constraint Alternative title ssim: EC 1141 Advisor Gerwick, William H. Remove constraint Advisor: Gerwick, William H. Degree Level Doctoral Remove constraint Degree Level: Doctoral

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  • Bioactive secondary metabolites from marine algae and study of oxidized anandamide derivatives

    Creator:
    Yoo, Hye-Dong
    Abstract:
    My investigations of the natural products of marine algae have resulted in the discovery of several new secondary metabolites. Bioassay-guided fractionation led to the isolation of these new compounds and spectroscopic analysis was utilized in their structural characterization. Two new and potent antimitotic metabolites, curacins B and C, were isolated...
    Resource Type:
    Dissertation
    Full Text:
    DEPT Distortion less Enhancement by Polarization Transfer DMSO Dimethylsulfoxide EC Effective

  • Novel oxylipins and other bioactive metabolites from marine algae

    Creator:
    Nagle, Dale George
    Abstract:
    I have participated in a drug discovery program designed to screen marine algae for inhibitors of cancer-related enzymes, antitumor compounds, antiinflammatory substances, and other agents of potential pharmaceutical utility. Over 1,500 lipid and aqueous extracts of marine plants and animals were surveyed for biomedical potential. Assays designed to screen extracts...
    Resource Type:
    Dissertation
    Full Text:
    DMSO Dimethylsulfoxide EC Effective Concentration EI Electron Impact EtOAc Ethyl Acetate FAB Fast