Index Catalog // ScholarsArchive@OSU

Development and application of NMR spectroscopy to marine natural products structure and biosynthesis

Creator:: Williamson, R. Thomas
Resource Type:: Dissertation
Full Text:: gratitude to Dr. William H. Gerwick for accepting me into his group and providing me with direction after

Biosynthesis and enzymology of conjugated polyenoic fatty acid production in macrophytic marine algae

Creator:: Wise, Mitchell L.
Resource Type:: Dissertation
Full Text:: Abstract approved: William H. Gerwick A novel enzyme, polyenoic fatty acid isomerase, which catalyzes the

Cloning and biochemical characterization of the hectochlorin biosynthetic gene cluster from the marine cyanobacterium Lyngbya majuscula

Creator:: Ramaswamy, Aishwarya V.
Abstract:: Cyanobacteria are rich in biologically active secondary metabolites, many of which have potential application as anticancer or antimicrobial drugs or as useful probes in cell biology studies. A Jamaican isolate of the marine cyanobacterium, Lyngbya majuscula was the source of a novel antifungal and cytotoxic secondary metabolite, hectochlorin. The structure...
Resource Type:: Dissertation
Full Text:: Lyngbya maluscula Abstract approved: William H. Gerwick Cyanobacteria are rich in biologically active

Biosynthesis, production and structural studies of secondary metabolites in cultured marine cyanobacteria

Creator:: Vulpanovici, Florina Alexandra
Abstract:: This thesis details investigations of marine cyanobacterial secondary metabolism, with emphasis on a strain of Phormidium sp. collected in Indonesia. These studies assessed the effects of nineteen putative elicitor compounds on the growth and metabolite production of five species of marine cyanobacteria, biosynthetic investigation of an intriguing secondary metabolite, phormidolide,...
Resource Type:: Dissertation
Full Text:: Abstract approved: William H. Gerwick This thesis details investigations of marine cyanobacterial

Structure and biosynthesis of marine cyanobacterial natural products : development and application of new NMR methods

Creator:: Marquez, Brian L.
Abstract:: This thesis is an account of my explorations into the field of natural products chemistry. These investigations led to the discovery of several novel secondary metabolites isolated from the marine cyanobacterium Lyngbya majuscula. In addition, biosynthetic investigations were undertaken using stable isotope-labeled precursors. The dominant role that NMR spectroscopy plays...
Resource Type:: Dissertation
Full Text:: Cyanobactenal Natural Products: Development and Application of New NMR Methods. Abstract approved: William H

Structure elucidation and biosynthetic investigations of marine cyanobacterial secondary metabolites

Creator:: Nogle, Lisa Marie
Abstract:: This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of thirteen new secondary metabolites, the isolation of over fifteen previously reported metabolites and the biosynthetic investigation of two additional cyanobacterial compounds. Two novel lipopeptides were identified from a Lyngbya majuscula and Schizothrix sp. assemblage...
Resource Type:: Dissertation
Full Text:: Biosynthetic Investigations of Marine Cyanobacterial Secondary Metabolites Abstract approved William H

Natural products studies of the marine cyanobacteria Lyngbya semiplena and Lyngbya majuscula

Creator:: Han, Bingnan
Abstract:: This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of eighteen new secondary metabolites. Isolation and characterization of these unique molecules were carried out using different chromatographic techniques and by careful analyses of 1D and 2D NMR data, respectively. Preliminary bioassays of the crude...
Resource Type:: Dissertation
Full Text:: gratitude to my major advisor, Dr. William Gerwick, and my committee members, Dr. Philip Proteau, Dr

New bioactive natural products from marine algae and cyanobacteria

Creator:: Sabry, Omar Mohamed
Abstract:: This thesis is an account of investigation on the natural products deriving from various marine algae and has resulted in the discovery of eleven novel bioactive metabolites. Isolation and characterization of these new molecules were carried out using different chromatographic techniques and by analyses of different spectroscopic data, respectively. Using...
Resource Type:: Dissertation
Full Text:: I would like to thank my major advisor, Dr. William H. Gerwick, for his exceptional generous

Natural products studies of the marine cyanobacterium Lyngbya majuscula

Creator:: Sitachitta, Namthip
Abstract:: The marine cyanobacterium Lyngbya majuscula has proven to be extraordinarily rich in bioactive secondary metabolites. This dissertation describes the chemistry of L. majuscula collected from Grenada, Fiji and Papua New Guinea, and the biosyntheses of two L. majuscula metabolites, curacin A and barbamide. The chemical studies with a Grenada collection...
Resource Type:: Dissertation
Full Text:: ------------ William H. Gerwick The marine cyanobacterium Lyngbya majuscula has proven to be extraordinarily rich

Natural products from tropical and temperate marine algae

Creator:: Bernart, Matthew W.
Abstract:: Following surveys of seaweeds in Oregon and the Caribbean, four algal species were selected for study on the basis of their crude extract biological activity or thin-layer chromatographic characteristics. Extracts were fractionated by normal phase chromatography, including high performance liquid chromatography (HPLC). Derivatives (methyl esters, acetates, and benzoates) of natural...
Resource Type:: Dissertation
Full Text:: Algae Abstract approved: Redacted for Privacy William H. Gerwick Following surveys of seaweeds in

ScholarsArchive@OSU

Development and application of NMR spectroscopy to marine natural products structure and biosynthesis

Biosynthesis and enzymology of conjugated polyenoic fatty acid production in macrophytic marine algae

Cloning and biochemical characterization of the hectochlorin biosynthetic gene cluster from the marine cyanobacterium Lyngbya majuscula

Biosynthesis, production and structural studies of secondary metabolites in cultured marine cyanobacteria

Structure and biosynthesis of marine cyanobacterial natural products : development and application of new NMR methods

Structure elucidation and biosynthetic investigations of marine cyanobacterial secondary metabolites

Natural products studies of the marine cyanobacteria Lyngbya semiplena and Lyngbya majuscula

New bioactive natural products from marine algae and cyanobacteria

Natural products studies of the marine cyanobacterium Lyngbya majuscula

Natural products from tropical and temperate marine algae

Limit your search

Academic Affiliation

Advisor

Commencement Year

Committee Member

Creator

Date

Decade

Degree Field

Degree Level

Degree Name

Language

License

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search