Search Constraints

Start Over
Filtering by: Alternative title ssim EC 546 Remove constraint Alternative title ssim: EC 546 Advisor Gerwick, William H. Remove constraint Advisor: Gerwick, William H. Language English [eng] Remove constraint Language: English [eng]

Search Results

  • The natural products chemistry of the red algae Ptilota filicina and Laurencia obtusa

    Creator:
    Lopez, Albert
    Abstract:
    The sea offers a wide variety of potentially useful resources. Marine algae have been a rich source of structurally unique natural products showing diverse biological properties. The current need to develop new antifungal, antibiotic, anticancer and antiviral drugs has prompted intense research efforts into the discovery, isolation and structure determination...
    Resource Type:
    Masters Thesis
    Full Text:
    subtilus; Ec = Escherichia coli, Pa = Pseudomonas aeruginosa; Ca = Candida albicans. The plates were

  • Novel icosanoids from the red marine alga Farlowia mollis

    Creator:
    Solem, Michele Lee
    Abstract:
    Farlowia mollis is a marine red alga that grows in the intertidal region along the coast of Oregon. We began studying the chemistry of this alga after a survey of Oregon seaweeds revealed possibly interesting chemistry and antimicrobial activity in its crude organic extract. Over the past three years the...
    Resource Type:
    Masters Thesis

  • Novel oxylipins and other bioactive metabolites from marine algae

    Creator:
    Nagle, Dale George
    Abstract:
    I have participated in a drug discovery program designed to screen marine algae for inhibitors of cancer-related enzymes, antitumor compounds, antiinflammatory substances, and other agents of potential pharmaceutical utility. Over 1,500 lipid and aqueous extracts of marine plants and animals were surveyed for biomedical potential. Assays designed to screen extracts...
    Resource Type:
    Dissertation
    Full Text:
    DMSO Dimethylsulfoxide EC Effective Concentration EI Electron Impact EtOAc Ethyl Acetate FAB Fast

  • Structure and biosynthesis of marine cyanobacterial natural products : development and application of new NMR methods

    Creator:
    Marquez, Brian L.
    Abstract:
    This thesis is an account of my explorations into the field of natural products chemistry. These investigations led to the discovery of several novel secondary metabolites isolated from the marine cyanobacterium Lyngbya majuscula. In addition, biosynthetic investigations were undertaken using stable isotope-labeled precursors. The dominant role that NMR spectroscopy plays...
    Resource Type:
    Dissertation