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Filtering by: Creator Nichols, Lowell Lewis Advisor Gerwick, William H. Rights Statement In Copyright

Natural products studies of the marine cyanobacteria Lyngbya semiplena and Lyngbya majuscula

Creator:

Han, Bingnan

Abstract:

This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of eighteen new secondary metabolites. Isolation and characterization of these unique molecules were carried out using different chromatographic techniques and by careful analyses of 1D and 2D NMR data, respectively. Preliminary bioassays of the crude...

Resource Type:

Dissertation
Biosynthesis, production and structural studies of secondary metabolites in cultured marine cyanobacteria

Creator:

Vulpanovici, Florina Alexandra

Abstract:

This thesis details investigations of marine cyanobacterial secondary metabolism, with emphasis on a strain of Phormidium sp. collected in Indonesia. These studies assessed the effects of nineteen putative elicitor compounds on the growth and metabolite production of five species of marine cyanobacteria, biosynthetic investigation of an intriguing secondary metabolite, phormidolide,...

Resource Type:

Dissertation
Structure elucidation and biosynthetic investigations of marine cyanobacterial secondary metabolites

Creator:

Nogle, Lisa Marie

Abstract:

This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of thirteen new secondary metabolites, the isolation of over fifteen previously reported metabolites and the biosynthetic investigation of two additional cyanobacterial compounds. Two novel lipopeptides were identified from a Lyngbya majuscula and Schizothrix sp. assemblage...

Resource Type:

Dissertation